Spin hyperpolarization in modern magnetic resonance
Magnetic resonance techniques are successfully utilized in a broad range of scientific
disciplines and in various practical applications, with medical magnetic resonance imaging …
disciplines and in various practical applications, with medical magnetic resonance imaging …
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
TR Alderson, LE Kay - Cell, 2021 - cell.com
Biomolecules are in constant motion. To understand how they function, and why
malfunctions can cause disease, it is necessary to describe their three-dimensional …
malfunctions can cause disease, it is necessary to describe their three-dimensional …
Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy
The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2)
highlights the need for coordinated research to combat COVID-19. A particularly important …
highlights the need for coordinated research to combat COVID-19. A particularly important …
Hyperpolarized water as universal sensitivity booster in biomolecular NMR
NMR spectroscopy is the only method to access the structural dynamics of biomolecules at
high (atomistic) resolution in their native solution state. However, this method's low …
high (atomistic) resolution in their native solution state. However, this method's low …
Room-temperature dynamic nuclear polarization enhanced NMR spectroscopy of small biological molecules in water
Nuclear magnetic resonance (NMR) spectroscopy is a powerful and popular technique for
probing the molecular structures, dynamics and chemical properties. However the …
probing the molecular structures, dynamics and chemical properties. However the …
Frémy's salt as a low-persistence hyperpolarization agent: efficient dynamic nuclear polarization plus rapid radical scavenging
Nuclear magnetic resonance (NMR) spectroscopy is a key technique for molecular structure
determination in solution. However, due to its low sensitivity, many efforts have been made …
determination in solution. However, due to its low sensitivity, many efforts have been made …
[HTML][HTML] NMR of RNA-structure and interactions
M Marušič, M Toplishek, J Plavec - Current Opinion in Structural Biology, 2023 - Elsevier
RNA was shown to have a more substantial role in the regulation of diverse cellular
processes than anticipated until recently. Answers to questions what is the structure of …
processes than anticipated until recently. Answers to questions what is the structure of …
Parahydrogen‐Induced Polarization of Amino Acids
AN Pravdivtsev, G Buntkowsky… - Angewandte Chemie …, 2021 - Wiley Online Library
Nuclear magnetic resonance (NMR) has become a universal method for biochemical and
biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging …
biomedical studies, including metabolomics, proteomics, and magnetic resonance imaging …
Discovery of RNA-targeted small molecules through the merging of experimental and computational technologies
EC Morishita - Expert Opinion on Drug Discovery, 2023 - Taylor & Francis
Introduction The field of RNA-targeted small molecules is rapidly evolving, owing to the
advances in experimental and computational technologies. With the identification of several …
advances in experimental and computational technologies. With the identification of several …
Toward protein NMR at physiological concentrations by hyperpolarized water—Finding and mapping uncharted conformational spaces
Nuclear magnetic resonance (NMR) spectroscopy is a key method for determining the
structural dynamics of proteins in their native solution state. However, the low sensitivity of …
structural dynamics of proteins in their native solution state. However, the low sensitivity of …