Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by dry mouth and
dry eyes, with lymphocytic infiltration of the exocrine glands. Saliva is becoming a useful tool …

OBJECTIVE: To analyse how the main components of the disease phenotype (sicca
symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by …

Objective The purpose of this study was to identify all outcome domains used in clinical
studies of xerostomia, that is, subjective sensation of dry mouth. This study is part of the …

Abstract Objective The novel Outcome Measures in Rheumatology Clinical Trials
(OMERACT) scoring system was used to evaluate the diagnostic effectiveness of major …

Purpose The lacrimal exocrinopathy of primary Sjögren's syndrome (pSS) is one of the main
causes of severe dry eye syndrome and a burden for patients. Early recognition and …

Background We sought to determine the most appropriate method for measuring salivary
flow to aid the diagnosis of Sjögren's syndrome (SS). Specifically, we compared the …

Primary Sjögren's Syndrome (pSS) is a multi-system autoimmune disease that involves the
exocrine glands. Lymphocytes infiltrate the gland tissue, leading to anatomical modification …

Objective The present study aimed to determine the salivary flow and metabolomic profile of
stimulated and unstimulated saliva in children. Materials and methods Children who …

Objective: Sjögren's Syndrome (SS) is a chronic inflammatory autoimmune exocrinopathy,
and although, the role of metabolism in the autoimmune responses has been discussed in …

Introduction Assessing labial salivary gland exocrinopathy is a cornerstone in primary
Sjögren's syndrome. Currently this relies on the histopathologic diagnosis of focal …