[HTML][HTML] The human virome: assembly, composition and host interactions

G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

[HTML][HTML] The lactoferrin phenomenon—a miracle molecule

P Kowalczyk, K Kaczyńska, P Kleczkowska… - Molecules, 2022 - mdpi.com
Numerous harmful factors that affect the human body from birth to old age cause many
disturbances, eg, in the structure of the genome, inducing cell apoptosis and their …

Intracellular pathogens: host immunity and microbial persistence strategies

A Thakur, H Mikkelsen… - Journal of immunology …, 2019 - Wiley Online Library
Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites
are ranked as the second leading cause of death worldwide by the World Health …

[HTML][HTML] Iron in immune cell function and host defense

D Haschka, A Hoffmann, G Weiss - Seminars in Cell & Developmental …, 2021 - Elsevier
The control over iron availability is crucial under homeostatic conditions and even more in
the case of an infection. This results from diverse properties of iron: first, iron is an important …

[HTML][HTML] Lactoferrin: a natural glycoprotein involved in iron and inflammatory homeostasis

L Rosa, A Cutone, MS Lepanto, R Paesano… - International journal of …, 2017 - mdpi.com
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by
exocrine glands and by neutrophils, is a key element of host defenses. HLf and bovine Lf …

[HTML][HTML] Human antimicrobial peptides as therapeutics for viral infections

A Ahmed, G Siman-Tov, G Hall, N Bhalla, A Narayanan - Viruses, 2019 - mdpi.com
Successful in vivo infection following pathogen entry requires the evasion and subversion of
multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune …

[HTML][HTML] Diverse mechanisms of antimicrobial activities of lactoferrins, lactoferricins, and other lactoferrin-derived peptides

Š Gruden, N Poklar Ulrih - International journal of molecular sciences, 2021 - mdpi.com
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the
mammalian body through their numerous functions, which include antimicrobial, antitumor …

[HTML][HTML] Lactoferrin in a context of inflammation-induced pathology

ML Kruzel, M Zimecki, JK Actor - Frontiers in immunology, 2017 - frontiersin.org
Much progress has been achieved to elucidate the function of lactoferrin (LTF), an iron-
binding glycoprotein, in the milieu of immune functionality. This review represents a unique …

[HTML][HTML] Lactoferrin's anti-cancer properties: Safety, selectivity, and wide range of action

A Cutone, L Rosa, G Ianiro, MS Lepanto… - Biomolecules, 2020 - mdpi.com
Despite recent advances in cancer therapy, current treatments, including radiotherapy,
chemotherapy, and immunotherapy, although beneficial, present attendant side effects and …

[HTML][HTML] Breast milk: A source of functional compounds with potential application in nutrition and therapy

C Sánchez, L Franco, P Regal, A Lamas, A Cepeda… - Nutrients, 2021 - mdpi.com
Breast milk is an unbeatable food that covers all the nutritional requirements of an infant in
its different stages of growth up to six months after birth. In addition, breastfeeding benefits …