Objective The crisis of prescription opioid (PO) related harms has focused attention toward
identifying and treating high-risk populations. This review aims to synthesize systematic …

Purpose This review sought to (a) describe definitions of long‐term opioid therapy (LTOT)
outcome measures, and (b) identify the predictors associated with the transition from short …

Background: Opioid use, abuse, and adverse consequences, including death, have
escalated at an alarming rate since the 1990s. In an attempt to control opioid abuse …

Multiple head-to-head trials have demonstrated that topical nonsteroidal anti-inflammatory
drugs (NSAIDs), including topical diclofenac, provide at least equivalent analgesia …

Bortezomib is a pivotal drug for the management of multiple myeloma. However, bortezomib
is a neurotoxic anticancer drug responsible for chemotherapy-induced peripheral …

Objectives: To determine the prevalence and factors associated with the use of opioids
among patients with chronic non-cancer pain (CNCP). Methods: A systematic review and …

Background Suboptimal medication adherence is a major reason for failure in the
management of major depressive disorder (MDD), childhood trauma might be an essential …

Purpose This study aimed to explore the effects of self-efficacy on adherence to self-
management and medication among patients with chronic diseases in China. Methods A …

Non-adherence is an important factor in therapeutic failure, which is frequently correlated
with disease progression. This phenomenon is common in most diseases that require …

Respect for patient autonomy and data privacy are generally accepted as foundational
western bioethical values. Nonetheless, as our society embraces expanding forms of …