Design, synthesis, docking study, and anticancer evaluation of novel bis-thiazole derivatives linked to benzofuran or benzothiazole moieties as PI3k inhibitors and …

IT Radwan, AHM Elwahy, AF Darweesh… - Journal of Molecular …, 2022 - Elsevier
A molecular hybridization approach was used to construct and develop a variety of new bis-
thiazoles coupled to benzofuran or benzothiazole moieties as anticancer drugs. The target …

Modular Approach to Benzofurans, 2H‐Chromenes and Benzoxepines via Claisen Rearrangement and Ring‐Closing Metathesis: Access to Phenylpropanoids

S Kotha, BU Solanke - Chemistry–An Asian Journal, 2022 - Wiley Online Library
Benzofurans, 2H‐chromenes and benzoxepines are key structural elements present in
several natural products and pharmaceuticals. Here, we describe an easy‐to‐execute …

Stitching Ynones with Nitromethanes: Domino Synthesis of Functionally Enriched Benzofurans and Benzothiophenes

S Singh, S Nerella, S Pabbaraja… - The Journal of Organic …, 2021 - ACS Publications
A convenient one-pot benzannulation of regioisomeric 2-or 3-substituted furan and
thiophene ynones with a range of nitromethanes has been discovered to directly access …

Design and synthesis of hetero-steroids via ring-closing metathesis: Biological studies towards in vitro anticancer activity

S Kotha, BU Solanke, PK Agarwala, S Kapoor - Steroids, 2022 - Elsevier
Here, we report a synthetic approach to hetero-steroids and also studied their biological
activities as anticancer agents. A novel class of oxacycles containing estrone moiety were …

[PDF][PDF] Anticancer activities of some heterocyclic compounds containing an oxygen atom: a review

SS Abbas, AM Jasim, TH Shakir, IS Abbas - Al-Rafidain Journal of Medical …, 2023 - iasj.net
The purpose of this study is to underline the progression and development of research
regarding oxygen-containing heterocycles, as well as to highlight the contribution that some …

Explorando las propiedades de la funga neotropical: perfil químico, actividades antioxidantes y antimicrobianas de Stiptophyllum erubescens (Berk.) Ryvarden

CRM Chaparro, D Benítez, Y Maubet, E Cristaldo… - 2023 - revistascientificas.una.py
Striptophyllum erubescens es un basidiomiceto neotropical distribuido ampliamente en
Sudamérica. Sin embargo, no se han encontrado registros de sus actividades biológicas …

Búsqueda de principios activos con potencial neuroprotector para el tratamiento de la enfermedad de alzheimer a partir de una especie del género Zanthoxylum …

AF Bustamante Romero - 2022 - repositorio.unal.edu.co
La Enfermedad de Alzheimer (EA) es la demencia más común, un desorden
neurodegenerativo de carácter multifactorial caracterizado por la presencia de placas …

[PDF][PDF] An Overview of the Phytochemistry and Pharmacological Effects of Benzofuran Derivatives

M Negi, M Yadav, R Singh, S Singh - afjbs.com
This overview's objective was to evaluate the efficacy of benzofuran derivatives, with a focus
on phytochemistry and pharmacological applications. The drug's phytochemistry …

[引用][C] In vivo Charakterisierung der antitumorigenen Effizienz von kaltem Atmosphärendruckplasma und small molecules am Modell des menschlichen Hautkrebses

M Kordt - 2022 - Dissertation, Rostock, Universität …