Hepatotoxicity due to herbal dietary supplements: Past, present and the future

BJ Gurley, MR McGill, I Koturbash - Food and Chemical Toxicology, 2022 - Elsevier
Dietary supplements (DS) constitute a widely used group of products comprising vitamin,
mineral, and botanical extract formulations. DS of botanical or herbal origins (HDS) …

Systems analysis of miRNA biomarkers to inform drug safety

AL Schofield, JP Brown, J Brown, A Wilczynska… - Archives of …, 2021 - Springer
Abstract microRNAs (miRNAs or miRs) are short non-coding RNA molecules which have
been shown to be dysregulated and released into the extracellular milieu as a result of many …

Impact of long-term supplementation with fish oil in individuals with non-alcoholic fatty liver disease: a double blind randomized placebo controlled clinical trial

K Cansanção, M Citelli, N Carvalho Leite… - Nutrients, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a chronic disease affecting up to 25% of the
population worldwide. n-3 long-chain polyunsaturated fatty acids (n-3 PUFA) have been …

Clinical impact of serum exosomal microRNA in liver fibrosis

Y Chang, JA Han, SM Kang, SW Jeong, T Ryu… - PloS one, 2021 - journals.plos.org
Background/aim We investigated alterations in the expression of serum exosomal miRNAs
with the progression of liver fibrosis and evaluated their clinical applicability as biomarkers …

Assessment of miR-103a-3p in leukocytes—No diagnostic benefit in combination with the blood-based biomarkers mesothelin and calretinin for malignant pleural …

C Jiménez-Ramírez, D Gilbert Weber… - Plos one, 2022 - journals.plos.org
Malignant pleural mesothelioma (MPM) is a cancer associated with asbestos exposure and
its diagnosis is challenging due to the moderate sensitivities of the available methods. In this …

Analysis of serum microRNA‐122 in a randomized controlled trial of N‐acetylcysteine for treatment of antituberculosis drug‐induced liver injury

MS Moosa, G Russomanno, JR Dorfman… - British Journal of …, 2023 - Wiley Online Library
Aim Serum microRNA‐122 (miR‐122) is a novel biomarker for drug‐induced liver injury,
with good sensitivity in the early diagnosis of paracetamol‐induced liver injury. We describe …

[HTML][HTML] Potential relative quantities of miR-122 and miR-150 to differentiate hepatocellular carcinoma from liver cirrhosis

NSA Gumilas, I Widodo, N Ratnasari… - Non-coding RNA …, 2022 - Elsevier
Cirrhosis and hepatocellular carcinoma (HCC) are related to chronic liver diseases.
Diagnostic algorithms are needed to discriminate HCC from cirrhosis for better patient …

Week-by-week changes in serum levels of bone-related circulating microRNAs and bone turnover markers

P Zarecki, F Gossiel, J Grillari, M Debono, M Hackl… - JBMR plus, 2024 - academic.oup.com
MicroRNAs are involved in post-transcriptional regulation of gene expression. Due to their
regulatory role, microRNAs are differently expressed during specific conditions in healthy …

Recent progress in the use of microRNAs as biomarkers for drug-induced toxicities in contrast to traditional biomarkers: A comparative review

S Oda, T Yokoi - Drug Metabolism and Pharmacokinetics, 2021 - Elsevier
Abstract microRNAs (miRNAs) are small non-coding RNAs with 18–25 nucleotides. They
play key regulatory roles in versatile biological process including development and …

[HTML][HTML] Dual Roles of microRNA-122 in Hepatocellular Carcinoma and Breast Cancer Progression and Metastasis: A Comprehensive Review

E Al Ageeli - Current Issues in Molecular Biology, 2024 - mdpi.com
microRNA-122 (miR-122) plays crucial yet contrasting roles in hepatocellular carcinoma
(HCC) and breast cancer (BC), two prevalent and aggressive malignancies. This review …