Neuron modeling may be said to have originated with the Hodgkin and Huxley action
potential model in 1952 and Rall's models of integrative activity of dendrites in 1964. Over …

Animals synchronize to the environmental day-night cycle by means of an internal circadian
clock in the brain. In mammals, this timekeeping mechanism is housed in the …

The brain is a hugely diverse, heterogeneous structure. Whether or not heterogeneity at the
neural level plays a functional role remains unclear, and has been relatively little explored in …

Sensory experience and perceptual learning changes receptive field properties of cortical
pyramidal neurons (PNs), largely mediated by synaptic long-term potentiation (LTP). The …

The hippocampal theta rhythm plays important roles in information processing; however, the
mechanisms of its generation are not well understood. We developed a data-driven …

Hippocampome. org is a comprehensive knowledge base of neuron types in the rodent
hippocampal formation (dentate gyrus, CA3, CA2, CA1, subiculum, and entorhinal cortex) …

The brain is composed of complex networks of interacting neurons that express
considerable heterogeneity in their physiology and spiking characteristics. How does this …

We developed a neural network model that can account for major elements common to
human focal seizures. These include the tonic-clonic transition, slow advance of clinical …

The extensive distribution and simultaneous termination of seizures across cortical areas
has led to the hypothesis that seizures are caused by large-scale coordinated networks …

Neuronal computation is achieved through connections of individual neurons into a larger
network. To expand the repertoire of endogenous cellular communication, we developed a …