Long-term synaptic plasticity is a major cellular substrate for learning, memory, and
behavioral adaptation. Although early examples of long-term synaptic plasticity described a …

Stem cell proliferation, neuronal differentiation, cell survival, and migration in the central
nervous system are all important steps in the normal process of neurogenesis. These …

The divalent cation zinc is an essential element, having both universal and specified
functions throughout the body. In the mammalian telencephalon, zinc has extensive effects …

Abstract (Figure Presented) Intracellular messaging: The novel two-photon fluorescent
probe ACa1 can visualize calcium waves in cells and living tissue for a long period of time …

Many cell types contain metal-ion unsaturated metallothionein (MT). Considering the Zn2+
binding affinity of metallothionein, the existence of this species in the intracellular …

The physiological role of synaptic zinc has remained largely enigmatic since its initial
detection in hippocampal mossy fibers over 50 years ago. The past few years have …

Aging is associated with decline in cognitive functions, prominently in the memory
consolidation and association capabilities. Hippocampus plays a crucial role in the …

Kainate receptors contribute to synaptic plasticity and rhythmic oscillatory firing of neurons in
corticolimbic circuits including hippocampal area CA3. We use zinc chelators and mice …

Reactive oxygen species (ROS) have an important role in cellular biology, being involved, in
a way that depends on their levels, in cell signaling processes or in oxidative stress …

The molecular mechanism of how reduced mobile zinc (Zn 2+) affected retinal ganglion cell
(RGC) survival and optic nerve regeneration after optic nerve crush (ONC) injury remains …