Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia
E Connell, G Le Gall, MG Pontifex, S Sami… - Molecular …, 2022 - Springer
A consequence of our progressively ageing global population is the increasing prevalence
of worldwide age-related cognitive decline and dementia. In the absence of effective …
of worldwide age-related cognitive decline and dementia. In the absence of effective …
Microbiota-derived metabolites as drivers of gut–brain communication
Alterations in the gut microbiota composition have been associated with a range of
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …
neurodevelopmental, neurodegenerative, and neuropsychiatric disorders. The gut microbes …
Role of diet and its effects on the gut microbiome in the pathophysiology of mental disorders
J Horn, DE Mayer, S Chen, EA Mayer - Translational psychiatry, 2022 - nature.com
There is emerging evidence that diet has a major modulatory influence on brain-gut-
microbiome (BGM) interactions with important implications for brain health, and for several …
microbiome (BGM) interactions with important implications for brain health, and for several …
Gut microbial molecules in behavioural and neurodegenerative conditions
BD Needham, R Kaddurah-Daouk… - Nature Reviews …, 2020 - nature.com
Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …
function. Gut–brain connections may be mediated by an assortment of microbial molecules …
[HTML][HTML] Interplay of gut microbiota and oxidative stress: Perspective on neurodegeneration and neuroprotection
S Shandilya, S Kumar, NK Jha, KK Kesari… - Journal of Advanced …, 2022 - Elsevier
Background Recent research on the implications of gut microbiota on brain functions has
helped to gather important information on the relationship between them. Pathogenesis of …
helped to gather important information on the relationship between them. Pathogenesis of …
The potential of metabolomics in biomedical applications
V Gonzalez-Covarrubias, E Martínez-Martínez… - Metabolites, 2022 - mdpi.com
The metabolome offers a dynamic, comprehensive, and precise picture of the phenotype.
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Current high-throughput technologies have allowed the discovery of relevant metabolites …
Implications of gut microbiota in neurodegenerative diseases
H Zhang, Y Chen, Z Wang, G Xie, M Liu… - Frontiers in …, 2022 - frontiersin.org
The morbidity associated with neurodegenerative diseases (NDs) is increasing, posing a
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …
threat to the mental and physical quality of life of humans. The crucial effect of microbiota on …
High-coverage metabolomics uncovers microbiota-driven biochemical landscape of interorgan transport and gut-brain communication in mice
The mammalian gut harbors a complex and dynamic microbial ecosystem: the microbiota.
While emerging studies support that microbiota regulates brain function with a few molecular …
While emerging studies support that microbiota regulates brain function with a few molecular …
Comprehensive metabolic profiling of Parkinson's disease by liquid chromatography-mass spectrometry
Background Parkinson's disease (PD) is a prevalent neurological disease in the elderly with
increasing morbidity and mortality. Despite enormous efforts, rapid and accurate diagnosis …
increasing morbidity and mortality. Despite enormous efforts, rapid and accurate diagnosis …
Microbiota-gut-brain axis: new therapeutic opportunities
C Long-Smith, KJ O'Riordan, G Clarke… - Annual review of …, 2020 - annualreviews.org
The traditional fields of pharmacology and toxicology are beginning to consider the
substantial impact our gut microbiota has on host physiology. The microbiota-gut-brain axis …
substantial impact our gut microbiota has on host physiology. The microbiota-gut-brain axis …