The preservation of nucleus structure during microscopy imaging is a top priority for
understanding chromatin organization, genome dynamics, and gene expression regulation …

The identification of causal genomic loci and their interactions underlying various traits in
plants has been greatly aided by progress in understanding the organization of the nuclear …

Background Retinal regenerative therapies hold great promise for the treatment of inherited
retinal degenerations (IRDs). Studies in preclinical lower mammal models of IRDs have …

The imaging of chromatin, genomic loci, RNAs, and proteins is very important to study their
localization, interaction, and coordinated regulation. Recently, several clustered regularly …

Development of live imaging techniques for providing information how chromatin is
organized in living cells is pivotal to decipher the regulation of biological processes. Here …

The intimate relationships between genome structure and function direct efforts toward
deciphering three-dimensional chromatin organization within the interphase nuclei at …

The 3D organization of chromatin plays an important role in genome stability and many
other pivotal biological programs. Therefore, the establishment of imaging methods, which …

Genome stability is constantly threatened by DNA lesions generated by different
environmental factors as well as endogenous processes. If not properly and timely repaired …

Visualizing the spatiotemporal organization of the genome will improve our understanding of
how chromatin structure and function are intertwined. Here, we describe a further …

Understanding the spatial organization of genomes within chromatin is crucial for
deciphering gene regulation. A recently developed CRISPR–dCas9-based genome labeling …