The promise of Synovial Joint-on-a-Chip in rheumatoid arthritis

X Zhang, R Su, H Wang, R Wu, Y Fan, Z Bin… - Frontiers in …, 2024 - frontiersin.org
Rheumatoid arthritis (RA) affects millions of people worldwide, but there are limited drugs
available to treat it, so acquiring a more comprehensive comprehension of the underlying …

[HTML][HTML] Role of Selenium in Pathogenesis and Treatment of the Autoimmune Diseases

E Rahmani, AM Fard, H Baghsheikhi, Z Hosseini… - Kindle, 2022 - preferpub.org
In vitro investigations have revealed that consumption of selenium can considerably
decrease the expression of IFN-g in Th1 cells. A low plasma selenium content has been …

Emerging Landscape of In Vitro Models for Assessing Rheumatoid Arthritis Management

AP Mishra, R Kumar, S Harilal, M Nigam… - ACS Pharmacology & …, 2024 - ACS Publications
Rheumatoid arthritis (RA) is a complex condition that is influenced by various causes,
including immunological, genetic, and environmental factors. Several studies using animal …

A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages

EML Philippon, LJE van Rooijen, F Khodadust… - Frontiers in …, 2023 - frontiersin.org
Objective Rheumatoid Arthritis (RA) is a progressive and systemic autoimmune disorder
associated with chronic and destructive joint inflammation. The hallmarks of joint synovial …

Large-scale high-throughput 3D culture, imaging, and analysis of cell spheroids using microchip-enhanced light-sheet microscopy

T Zhu, J Nie, T Yu, D Zhu, Y Huang, Z Chen… - Biomedical Optics …, 2023 - opg.optica.org
Light sheet microscopy combined with a microchip is an emerging tool in biomedical
research that notably improves efficiency. However, microchip-enhanced light-sheet …

Investigating the Combined Effects of Mechanical Stress and Nutrition on Muscle Hypertrophic Signals Using Contractile 3D-Engineered Muscle (3D-EM)

D Yi, T Sugimoto, T Matsumura, S Yokoyama… - Nutrients, 2023 - mdpi.com
Since 3D-EM closely resembles in vivo muscles, the aim of this study was to investigate the
effects of exercise (electrical pulse stimulation (EPS)) and nutrition (maca), which contains …

Cell Cultures as a Versatile Tool in the Research and Treatment of Autoimmune Connective Tissue Diseases

A Ejma-Multański, A Wajda, A Paradowska-Gorycka - Cells, 2023 - mdpi.com
Cell cultures are an important part of the research and treatment of autoimmune connective
tissue diseases. By culturing the various cell types involved in ACTDs, researchers are able …

Anti-inflammatory and anti-rheumatic effects of Phoenix dactylifera L.(date palm) seed by controlling cytokines and inhibiting JAK1/STAT3 pathway on CFA-induced …

ZA El-Gendy, S Abdelazeem, GAA Jaleel, ME Ali… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Phoenix dactylifera L.(date palm) seed is widely used in
Arabian traditional medicine to alleviate several health problems including inflammatory …

[HTML][HTML] 3D Culture of MSCs for Clinical Application

Q Gao, MS Cekuc, YS Ergul, AK Pius, I Shinohara… - Bioengineering, 2024 - mdpi.com
Mesenchymal stem cells (MSCs) play an important role in regenerative medicine and drug
discovery due to their multipotential differentiation capabilities and immunomodulatory …

2D and 3D culture of stem cells

K Bieńko, M Leszcz, J Białek… - Journal of Education …, 2023 - apcz.umk.pl
Wstęp i cel: Komórki macierzyste są szeroko stosowane w wielu naukach, szczególnie w
chorobach. Dzięki swoim właściwościom proliferacyjnym i zdolności do tworzenia się w …