[HTML][HTML] Current State of Therapeutics for HTLV-1

TT Wang, A Hirons, M Doerflinger, KV Morris… - …, 2024 - pmc.ncbi.nlm.nih.gov
Human T cell leukaemia virus type-1 (HTLV-1) is an oncogenic retrovirus that causes
lifelong infection in~ 5–10 million individuals globally. It is endemic to certain First Nations …

Epigenetic control of multiple genes with a lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays

D Monteferrario, M David, SK Tadi, Y Zhou… - … Therapy Methods & …, 2024 - cell.com
Gene silencing without gene editing holds great potential for the development of safe
therapeutic applications. Here, we describe a novel strategy to concomitantly repress …