Hyaluronan and cardiac regeneration

F Bonafè, M Govoni, E Giordano, CM Caldarera… - Journal of biomedical …, 2014 - Springer
Hyaluronan (HA) is abundantly expressed in several human tissues and a variety of roles for
HA has been highlighted. Particularly relevant for tissue repair, HA is actively produced …

A novel model of cancer drug resistance: oncosomal release of cytotoxic and antibody-based drugs

T Eguchi, EA Taha, SK Calderwood, K Ono - Biology, 2020 - mdpi.com
Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic
molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor …

Resveratrol mediates the miR-149/HMGB1 axis and regulates the ferroptosis pathway to protect myocardium in endotoxemia mice

X Wang, A Simayi, J Fu, X Zhao… - American Journal of …, 2022 - journals.physiology.org
Endotoxemia is a common complication often used to model the acute inflammatory
response associated with endotoxemia. Resveratrol has been shown to exert a wide range …

Sodium butyrate attenuates angiotensin II‐induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6‐dependent mechanism

L Zhang, M Deng, A Lu, Y Chen, Y Chen… - Journal of Cellular …, 2019 - Wiley Online Library
Sodium butyrate (NaBu) is reported to play important roles in a number of chronic diseases.
The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II) …

HIF‐2α suppresses p53 to enhance the stemness and regenerative potential of human embryonic stem cells

B Das, R Bayat‐Mokhtari, M Tsui, S Lotfi… - Stem …, 2012 - academic.oup.com
Human embryonic stem cells (hESCs) have been reported to exert cytoprotective activity in
the area of tissue injury. However, hypoxia/oxidative stress prevailing in the area of injury …

Astragaloside IV-induced BMSC exosomes promote neovascularization and protect cardiac function in myocardial infarction mice via the miR-411/HIF-1α axis

L Yang, N Liu, Y Yang - Journal of Liposome Research, 2024 - Taylor & Francis
This study focused on investigating the mechanism of the astragaloside IV-induced bone
marrow mesenchymal stem cell exosome (AS-IV-MSC-exo)/microRNA (miR)-411/HIF-1α …

Ferritin as a reporter gene for in vivo tracking of stem cells by 1.5-T cardiac MRI in a rat model of myocardial infarction

M Campan, V Lionetti, GD Aquaro… - American Journal …, 2011 - journals.physiology.org
The methods currently utilized to track stem cells by cardiac MRI are affected by important
limitations, and new solutions are needed. We tested human ferritin heavy chain (hFTH) as a …

[PDF][PDF] RETRACTED: Silencing CircHIPK3 Sponges miR-93-5p to Inhibit the Activation of Rac1/PI3K/AKT Pathway and Improves Myocardial Infarction-Induced …

Y Wu, M Wu, J Yang, Y Li, W Peng, M Wu… - Frontiers in …, 2021 - frontiersin.org
The ceRNA network involving circular RNAs (circRNAs) is essential in the cardiovascular
system. We investigated the underlying ceRNA network involving circHIPK3 in myocardial …

Cardiomyocyte-targeting exosomes from sulforaphane-treated fibroblasts affords cardioprotection in infarcted rats

G Papini, G Furini, M Matteucci, V Biemmi… - Journal of Translational …, 2023 - Springer
Abstract Background Exosomes (EXOs), tiny extracellular vesicles that facilitate cell–cell
communication, are being explored as a heart failure treatment, although the features of the …

Barley beta‐glucan promotes MnSOD expression and enhances angiogenesis under oxidative microenvironment

S Agostini, E Chiavacci, M Matteucci… - Journal of Cellular …, 2015 - Wiley Online Library
Manganese superoxide dismutase (MnSOD), a foremost antioxidant enzyme, plays a key
role in angiogenesis. Barley‐derived (1.3) β‐d‐glucan (β‐d‐glucan) is a natural water …