Smart dry powder inhalers and intelligent adherence management

S Häußermann, LJ Arendsen, JN Pritchard - Advanced drug delivery …, 2022 - Elsevier
Adherence to inhaled treatments is a complex challenge for patients with chronic obstructive
pulmonary disease (COPD) and asthma, it not only involves following the prescribed …

Advances in audio-based systems to monitor patient adherence and inhaler drug delivery

TE Taylor, Y Zigel, C De Looze, I Sulaiman… - Chest, 2018 - Elsevier
Hundreds of millions of people worldwide have asthma and COPD. Current medications to
control these chronic respiratory diseases can be administered using inhaler devices, such …

Irregular and ineffective: a quantitative observational study of the time and technique of inhaler use

I Sulaiman, J Seheult, E MacHale, S D'Arcy… - The Journal of Allergy …, 2016 - Elsevier
Background Cross-sectional observational studies suggest that between 50% and 60% of
patients misuse a dry powder inhaler, whereas studies with electronic monitors indicate that …

Hold the device against the skin: the impact of injection duration on user's force for handheld autoinjectors

A Schneider, P Mueller, C Jordi, P Richard… - Expert opinion on …, 2020 - Taylor & Francis
Background: The recent development of high-volume subcutaneous drug delivery using
handheld autoinjectors has resulted in longer injection durations. However, the usability of …

Objective assessment of patient inhaler user technique using an audio-based classification approach

TE Taylor, Y Zigel, C Egan, F Hughes, RW Costello… - Scientific reports, 2018 - nature.com
Many patients make critical user technique errors when using pressurised metered dose
inhalers (pMDIs) which reduce the clinical efficacy of respiratory medication. Such critical …

The impact of common inhaler errors on drug delivery: investigating critical errors with a dry powder inhaler

I Sulaiman, J Seheult, N Sadasivuni… - Journal of aerosol …, 2017 - liebertpub.com
Background: Researchers, using checklists, have identified that 30%–90% of patients make
errors in inhaler use. It is not certain whether these errors affect the delivery of medication …

Estimation of inhalation flow profile using audio-based methods to assess inhaler medication adherence

TE Taylor, H Lacalle Muls, RW Costello, RB Reilly - PloS one, 2018 - journals.plos.org
Asthma and chronic obstructive pulmonary disease (COPD) patients are required to inhale
forcefully and deeply to receive medication when using a dry powder inhaler (DPI). There is …

[HTML][HTML] Flowrate Sensing and Measurement in Portable Smart Inhalers

I Mysovskikh, M Legg, S Demidenko - Sensors, 2024 - mdpi.com
This review discusses approaches and implementations of flowrate sensing and
measurement in smart inhalers for effective respiratory disease management. It highlights …

A novel statistical method for assessing effective adherence to medication and calculating optimal drug dosages

G Greene, RW Costello, B Cushen, I Sulaiman… - PLoS …, 2018 - journals.plos.org
Objective We derive a novel model-based metric for effective adherence to medication, and
validate it using data from the INhaler Compliance Assessment device (INCATM). This …

A Review of Sensor-Based Interventions for Supporting Patient Adherence to Inhalation Therapy

J Ma, X Sun, B Liu - Patient preference and adherence, 2024 - Taylor & Francis
Purpose This review aims to provide a comprehensive overview of sensor technologies
employed in interventions to enhance patient adherence to inhalation therapy for chronic …