Multi-lineage human iPSC-derived platforms for disease modeling and drug discovery

A Sharma, S Sances, MJ Workman, CN Svendsen - Cell stem cell, 2020 - cell.com
Human induced pluripotent stem cells (hiPSCs) provide a powerful platform for disease
modeling and have unlocked new possibilities for understanding the mechanisms governing …

Polycaprolactone usage in additive manufacturing strategies for tissue engineering applications: A review

EH Backes, SV Harb, CAG Beatrice… - … Research Part B …, 2022 - Wiley Online Library
Polycaprolactone (PCL) has been extensively applied on tissue engineering because of its
low‐melting temperature, good processability, biodegradability, biocompatibility, mechanical …

Emulating human tissues and organs: a bioprinting perspective toward personalized medicine

AC Fonseca, FPW Melchels, MJS Ferreira… - Chemical …, 2020 - ACS Publications
The lack of in vitro tissue and organ models capable of mimicking human physiology
severely hinders the development and clinical translation of therapies and drugs with higher …

3D printing of bioceramic scaffolds—barriers to the clinical translation: from promise to reality, and future perspectives

K Lin, R Sheikh, S Romanazzo, I Roohani - Materials, 2019 - mdpi.com
In this review, we summarize the challenges of the three-dimensional (3D) printing of porous
bioceramics and their translational hurdles to clinical applications. The state-of-the-art of the …

Cardiac tissues from stem cells: new routes to maturation and cardiac regeneration

G Campostrini, LM Windt, BJ van Meer… - Circulation …, 2021 - Am Heart Assoc
The ability of human pluripotent stem cells to form all cells of the body has provided many
opportunities to study disease and produce cells that can be used for therapy in …

Stem cells for next level toxicity testing in the 21st century

E Fritsche, T Haarmann‐Stemmann, J Kapr, S Galanjuk… - Small, 2021 - Wiley Online Library
The call for a paradigm change in toxicology from the United States National Research
Council in 2007 initiates awareness for the invention and use of human‐relevant alternative …

Large‐scale production of wholly cellular bioinks via the optimization of human induced pluripotent stem cell aggregate culture in automated bioreactors

DLL Ho, S Lee, J Du, JD Weiss, T Tam… - Advanced …, 2022 - Wiley Online Library
Combining the sustainable culture of billions of human cells and the bioprinting of wholly
cellular bioinks offers a pathway toward organ‐scale tissue engineering. Traditional 2D …

Application of 3D bioprinters for dental pulp regeneration and tissue engineering (porous architecture)

P Iranmanesh, A Ehsani, A Khademi… - Transport in Porous …, 2022 - Springer
One of the well-known ways to produce porous scaffolds or special three-dimensional (3D)
micro-nanostructures is using the 3D printing technique. This technique requires a suitable …

Stem cell-derived extracellular vesicles for cancer therapy and tissue engineering applications

CS Lee, M Lee, K Na, HS Hwang - Molecular Pharmaceutics, 2023 - ACS Publications
Recently, stem cells and their secretomes have attracted great attention in biomedical
applications, particularly extracellular vesicles (EVs). EVs are secretomes of cells for cell-to …

Fundamentals of light-cell–polymer interactions in photo-cross-linking based bioprinting

D Nieto, JA Marchal Corrales, A Jorge de Mora… - APL …, 2020 - pubs.aip.org
Biofabrication technologies that use light for polymerization of biomaterials have made
significant progress in the quality, resolution, and generation of precise complex tissue …