It is widely accepted that β-amyloid oligomers (Aβos) play a key role in the progression of
Alzheimer's disease (AD) by inducing neuron damage and cognitive impairment, but Aβos …

The p75 neurotrophin receptor (p75 NTR) functions at the molecular nexus of cell death,
survival, and differentiation. In addition to its contribution to neurodegenerative diseases and …

Oxidative stress and apoptosis play a key role in the pathogenesis of sepsis‐associated
acute kidney injury (AKI). Dexmedetomidine (DEX) may present renal protective effects in …

Although epidemiological studies indicate that sleep-disordered breathing (SDB) such as
obstructive sleep apnea is a strong risk factor for the development of Alzheimer's disease …

The family of VPS10p-Domain (D) receptors comprises five members named SorLA, Sortilin,
SorCS1, SorCS2 and SorCS3. While their physiological roles remain incompletely resolved …

Background Although a large amount of evidence has revealed that amyloid β (Aβ),
especially Aβ oligomers, protofibrils, and pyroglutamated Aβs, participate primarily in the …

Synapse and dendritic spine loss induced by amyloid-β oligomers is one of the main
hallmarks of the early phases of Alzheimer's disease (AD) and is directly correlated with the …

Degeneration of basal forebrain cholinergic neurons (BFCNs) is a hallmark of Alzheimer's
disease (AD). However, few mouse models of AD recapitulate the neurodegeneration of the …

Age‐induced impairments in learning and memory are in part caused by changes to
hippocampal synaptic plasticity during aging. The p75 neurotrophin receptor (p75NTR) and …

Cholinergic basal forebrain (cBF) neurons are defined by their expression of the p75
neurotrophin receptor (p75NTR) and tropomyosin-related kinase (Trk) neurotrophin …