[HTML][HTML] Exploring epigenetic modifications as potential biomarkers and therapeutic targets in glaucoma
E Tonti, R Dell'Omo, M Filippelli, L Spadea… - International Journal of …, 2024 - mdpi.com
Glaucoma, a complex and multifactorial neurodegenerative disorder, is a leading cause of
irreversible blindness worldwide. Despite significant advancements in our understanding of …
irreversible blindness worldwide. Despite significant advancements in our understanding of …
[HTML][HTML] MicroRNAs in Pancreatic Cancer: Advances in Biomarker Discovery and Therapeutic Implications
Pancreatic cancer remains a formidable malignancy characterized by high mortality rates,
primarily attributable to late-stage diagnosis and a dearth of effective therapeutic …
primarily attributable to late-stage diagnosis and a dearth of effective therapeutic …
[HTML][HTML] miR-6805-5p as a biomarker of cisplatin-induced nephrotoxicity in patients with head and neck cancer
NDG Torso, JCF Quintanilha, MA Cursino… - Frontiers in …, 2023 - frontiersin.org
Introduction: The standard treatment for head and neck squamous cell carcinoma (HNSCC)
is cisplatin chemoradiotherapy. One of the main treatment adverse reactions is …
is cisplatin chemoradiotherapy. One of the main treatment adverse reactions is …
[HTML][HTML] The TGFβ Induced MicroRNAome of the Trabecular Meshwork
C Doyle, B Callaghan, AW Roodnat, L Armstrong… - Cells, 2024 - mdpi.com
Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with a complex,
multifactorial aetiology. Raised intraocular pressure (IOP) is the most important clinically …
multifactorial aetiology. Raised intraocular pressure (IOP) is the most important clinically …
Silencing circRUFY1 protects retinal ganglion cell injury in acute intraocular hypertension by activating the ERK pathway through miR-196a-5p/CALM3 axis
BB Li, SJ Li, W Tang, M Zeng - Molecular & Cellular Toxicology, 2024 - Springer
Background Neuroinflammation has been recognized as a key pathological event in acute
glaucoma. Medical treatment of acute glaucoma has mainly focused on lowering intraocular …
glaucoma. Medical treatment of acute glaucoma has mainly focused on lowering intraocular …
TGF-beta/OPTN/FOXC1/miR-200 axis regulates intraocular pressure dynamics in trabecular meshwork cells
Glaucoma is the second leading cause of irreversible blindness globally, with elevated
intraocular pressure (IOP) being its primary risk factor. Current therapeutic approaches, such …
intraocular pressure (IOP) being its primary risk factor. Current therapeutic approaches, such …
miR-210 is essential to retinal homeostasis in fruit flies and mice
D Colaianni, F Virga, A Tisi, C Stefanelli, G Zaccagnini… - bioRxiv, 2024 - biorxiv.org
miR-210 is one of the most evolutionarily conserved microRNAs. Recent studies in
Drosophila melanogaster have unveiled that the absence of miR-210 leads to a progressive …
Drosophila melanogaster have unveiled that the absence of miR-210 leads to a progressive …
[PDF][PDF] Investigating the therapeutic efficacy and mechanism of action of microRNAs in ameliorating Diabetic wounds
S Paul - 2023 - ourarchive.otago.ac.nz
Diabetes mellitus is a chronic disease and is responsible for the development of several
complications, such as diabetic wounds. Diabetic wound healing is characterized by an …
complications, such as diabetic wounds. Diabetic wound healing is characterized by an …