Alterations of functional network connectivity have been implicated in the pathophysiology of
schizophrenia (SCZ) and bipolar disorder (BD). Recent studies also suggest that the …

Objectives Magnetic resonance imaging (MRI) studies comparing bipolar and unipolar
depression characterize pathophysiological differences between these conditions. However …

Background Both childhood trauma and disruptions in brain functional networks are
implicated in the development of psychiatric disorders in early adulthood. However, the …

Symptomatic overlap of depressive episodes in bipolar disorder (BD) and major depressive
disorder (MDD) is a major diagnostic and therapeutic problem. Mania in medical history …

Background: Major depressive disorder (MDD) has demonstrated abnormalities of static
intrinsic brain activity measured by amplitude of low-frequency fluctuation (ALFF). Recent …

Background As a neuroprogressive illness, depression is accompanied by brain structural
abnormality that extends to many brain regions. However, the progressive structural …

Spontaneous fluctuations in the blood oxygenation level dependent signal measured
through resting-state functional magnetic resonance imaging have been corroborated to …

Background When bipolar disorder (BD) presents as the depressive state, it is often
misdiagnosed as major depressive disorder (MDD). However, few studies have focused on …

Objective There is no objective method to diagnose major depressive disorder (MDD). This
study explored the neuroimaging biomarkers using the support vector machine (SVM) …

Early life stress (ELS) and major depressive disorder (MDD) share neural network
abnormalities. However, it is unclear how ELS and MDD may separately and/or jointly relate …