[HTML][HTML] Role of transient receptor potential vanilloid 4 in vascular function

L Liu, M Guo, X Lv, Z Wang, J Yang, Y Li… - Frontiers in molecular …, 2021 - frontiersin.org
Transient receptor potential vanilloid 4 (TRPV4) channels are widely expressed in systemic
tissues and can be activated by many stimuli. TRPV4, a Ca2+-permeable cation channel …

[HTML][HTML] Cannabinoids—A New Perspective in Adjuvant Therapy for Pulmonary Hypertension

A Krzyżewska, M Baranowska-Kuczko… - International Journal of …, 2021 - mdpi.com
Currently, no treatment can completely cure pulmonary hypertension (PH), which can lead to
right ventricular failure and, consequently, death. Therefore, searching for new therapies …

[HTML][HTML] Bidirectional TRP/L Type Ca2+ Channel/RyR/BKCa Molecular and Functional Signaloplex in Vascular Smooth Muscles

DO Dryn, MI Melnyk, D Melanaphy, IV Kizub… - Biomolecules, 2023 - mdpi.com
TRP channels are expressed both in vascular myocytes and endothelial cells, but
knowledge of their operational mechanisms in vascular tissue is particularly limited. Here …

[PDF][PDF] The role of mechanosensitive TRPV4 channels in the regulation of myometrium spontaneous and oxytocin-induced contractility under normal and …

OF Moroz, OO Drozd, RT Lavryk, IO Lazorenko… - 2022 - scholar.archive.org
Pharmacological modulators of TRPV4 activity were examined in the rat and human
myometrial tissue as the potential drugs with the perspective of attenuation of premature …

[PDF][PDF] Evaluation of the component's contribution in endothelium-dependent acetylcholine-induced relaxation of the rat aorta.

OR Mezhenskyi, IB Philyppov - Physiological Journal/Fiziologichnyi …, 2024 - fz.kiev.ua
The regulation of rat aorta vascular tone involves various factors, including endothelium-
derived hyperpolarization factor (EDHF), nitric oxide (NO), prostaglandins, and sensory …

[PDF][PDF] Пригнічувальна дія загального анестетика кетаміну на транзієнти внутрішньоклітинної концентрації іонів кальцію та скорочення гладеньком'язових …

МІ Мельник, ДО Дринь, ДО Дзюба… - Physiological Journal …, 2023 - fz.kiev.ua
Механізми негативних наслідків дії загальних анестетиків на гладеньких м'язах
практично не вивчалися. Мета нашої роботи–дослідити вплив загального анестетика …