Pesticides: an update of human exposure and toxicity

S Mostafalou, M Abdollahi - Archives of toxicology, 2017 - Springer
Pesticides are a family of compounds which have brought many benefits to mankind in the
agricultural, industrial, and health areas, but their toxicities in both humans and animals …

Organic cation transporters in health and disease

H Koepsell - Pharmacological reviews, 2020 - ASPET
The organic cation transporters (OCTs) OCT1, OCT2, OCT3, novel OCT (OCTN) 1, OCTN2,
multidrug and toxin exclusion (MATE) 1, and MATE kidney-specific 2 are polyspecific …

[HTML][HTML] Neurotoxicity of pesticides–A link to neurodegeneration

B Vellingiri, M Chandrasekhar, SS Sabari… - Ecotoxicology and …, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative disorder which mainly targets motor
symptoms such as tremor, rigidity, bradykinesia and postural instability. The physiological …

Pesticides and human chronic diseases: evidences, mechanisms, and perspectives

S Mostafalou, M Abdollahi - Toxicology and applied pharmacology, 2013 - Elsevier
Along with the wide use of pesticides in the world, the concerns over their health impacts are
rapidly growing. There is a huge body of evidence on the relation between exposure to …

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

SR Subramaniam, MF Chesselet - Progress in neurobiology, 2013 - Elsevier
Parkinson's disease (PD) is a movement disorder that is characterized by the progressive
degeneration of dopaminergic neurons in substantia nigra pars compacta resulting in …

[HTML][HTML] An update on the diagnosis and treatment of Parkinson disease

P Rizek, N Kumar, MS Jog - Cmaj, 2016 - Can Med Assoc
Methods We used Canadian and American national guidelines to inform this review, in
addition to published systematic reviews that were known to us. We identified additional …

[HTML][HTML] Association between Parkinson's disease and cigarette smoking, rural living, well-water consumption, farming and pesticide use: systematic review and meta …

CB Breckenridge, C Berry, ET Chang, RL Sielken Jr… - PloS one, 2016 - journals.plos.org
Objective Bradford Hill's viewpoints were used to conduct a weight-of-the-evidence
assessment of the association between Parkinson's disease (PD) and rural living, farming …

A guide to neurotoxic animal models of Parkinson's disease

K Tieu - Cold Spring Harbor perspectives in …, 2011 - perspectivesinmedicine.cshlp.org
Parkinson's disease (PD) is a neurological movement disorder primarily resulting from
damage to the nigrostriatal dopaminergic pathway. To elucidate the pathogenesis …

[HTML][HTML] Environmental exposures and Parkinson's disease

S Nandipati, I Litvan - International journal of environmental research and …, 2016 - mdpi.com
Parkinson's disease (PD) affects millions around the world. The Braak hypothesis proposes
that in PD a pathologic agent may penetrate the nervous system via the olfactory bulb, gut …

The role of environmental exposures in neurodegeneration and neurodegenerative diseases

JR Cannon, JT Greenamyre - Toxicological Sciences, 2011 - academic.oup.com
Neurodegeneration describes the loss of neuronal structure and function. Numerous
neurodegenerative diseases are associated with neurodegeneration. Many are rare and …