Restoring synaptic function: how intranasal delivery of 3D-cultured hUSSC exosomes improve learning and memory deficits in Alzheimer's disease

M Pourhadi, H Zali, R Ghasemi, M Faizi, F Mojab… - Molecular …, 2024 - Springer
Memory problems are often the first signs of cognitive impairment related to Alzheimer's
disease (AD), and stem cells and stem cell-derived exosomes (EXOs) have been studied for …

Building Natural Product–Based Libraries for Drug Discovery: Challenges and Opportunities from a Brazilian Pharmaceutical Industry Perspective

GG Conrado, R da Rosa, RD Reis… - Revista Brasileira de …, 2024 - Springer
Natural products represent an important source of new leads in drug discovery research.
Several drugs currently used as therapeutic agents have been developed from natural …

[PDF][PDF] 菟丝子及其有效成分治疗阿尔茨海默病的药理机理研究进展

方永光, 王莎, 代欣旖, 姚景瑞, 王颍, 高伶俪, 徐冰 - 江苏中医药, 2024 - jstcm.cn
摘要阿尔茨海默病(AD) 俗称老年性痴呆, 是一种以患者的记忆障碍, 人格改变,
认知障碍等为主要临床表现的神经系统退行性疾病, 其起病隐匿, 病因不明, 发病机制复杂 …