Synthetic biology applies genetic tools to engineer living cells and organisms analogous to
the programming of machines. In materials synthetic biology, engineering principles from …

Bacterial genomes encode the biosynthetic potential to produce hundreds of thousands of
complex molecules with diverse applications, from medicine to agriculture and materials …

INTRODUCTION Cells respond to their environment, make decisions, build structures, and
coordinate tasks. Underlying these processes are computational operations performed by …

Rapid advances in synthetic biology are driving the development of genetically engineered
microbes as therapeutic agents for a multitude of human diseases, including cancer. The …

For over 60 years, the synthetic production of new DNA sequences has helped researchers
understand and engineer biology. Here we summarize methods and caveats for the de novo …

Cells navigate environments, communicate and build complex patterns by initiating gene
expression in response to specific signals. Engineers seek to harness this capability to …

There is an immediate need to drastically reduce the emissions associated with global fossil
fuel consumption in order to limit climate change. However, carbon-based materials …

Legumes obtain nitrogen from air through rhizobia residing in root nodules. Some species of
rhizobia can colonize cereals but do not fix nitrogen on them. Disabling native regulation …

Despite enormous progress in understanding the fundamentals of bacterial gene regulation,
our knowledge remains limited when compared with the number of bacterial genomes and …

Communities of microbes play important roles in natural environments and hold great
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …