Hydroxyapatite nanoparticles for improved cancer theranostics

S Kargozar, S Mollazadeh, F Kermani… - Journal of Functional …, 2022 - mdpi.com
Beyond their well-known applications in bone tissue engineering, hydroxyapatite
nanoparticles (HAp NPs) have also been showing great promise for improved cancer …

Non‐coding RNAs in cancer immunotherapy: Predictive biomarkers and targets

M Alahdal, E Elkord - Clinical and translational medicine, 2023 - Wiley Online Library
Background To date, standardising clinical predictive biomarkers for assessing the response
to immunotherapy remains challenging due to variations in personal genetic signatures …

Extracellular vesicle PD-L1 dynamics predict durable response to immune-checkpoint inhibitors and survival in patients with non-small cell lung cancer

D de Miguel-Perez, A Russo, O Arrieta, M Ak… - Journal of Experimental …, 2022 - Springer
Abstract Background Immune-checkpoint inhibitors (ICIs) changed the therapeutic
landscape of patients with lung cancer. However, only a subset of them derived clinical …

Definition, incidence, and challenges for assessment of hyperprogressive disease during cancer treatment with immune checkpoint inhibitors: a systematic review and …

HJ Park, KW Kim, SE Won, S Yoon, YK Chae… - JAMA network …, 2021 - jamanetwork.com
Importance Hyperprogressive disease (HPD) is a recognized pattern of rapid tumor
progression during immune checkpoint inhibitor (ICI) treatment. Definitions of HPD have not …

Non-small-cell lung cancer signaling pathways, metabolism, and PD-1/PD-L1 antibodies

M Santarpia, A Aguilar, I Chaib, AF Cardona, S Fancelli… - Cancers, 2020 - mdpi.com
Treatment of advanced (metastatic) non-small-cell lung cancer (NSCLC) is currently mainly
based on immunotherapy with antibodies against PD-1 or PD-L1, alone, or in combination …

Associations between dysbiosis-inducing drugs, overall survival and tumor response in patients treated with immune checkpoint inhibitors

L Gaucher, L Adda, A Séjourné… - … in medical oncology, 2021 - journals.sagepub.com
Background: There are conflicting data on the effects of dysbiosis-inducing drugs, and
especially antibiotics (ATBs), on clinical outcomes in patients treated with immune …

Large-scale profiling of extracellular vesicles identified miR-625-5p as a novel biomarker of immunotherapy response in advanced non-small-cell lung cancer patients

F Pantano, F Zalfa, M Iuliani, S Simonetti, P Manca… - Cancers, 2022 - mdpi.com
Simple Summary Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of
advanced non-small-cell lung cancer (NSCLC) leading to substantial improvement in …

Immunotherapy for metastatic non-small cell lung cancer: therapeutic advances and biomarkers

M Russano, G La Cava, A Cortellini, F Citarella… - Current …, 2023 - mdpi.com
Immunotherapy has revolutionized the treatment paradigm of non-small cell lung cancer and
improved patients' prognosis. Immune checkpoint inhibitors have quickly become standard …

The Essential Oil of Cymbopogon citratus Stapt and Carvacrol: An Approach of the Antitumor Effect on 7,12-Dimethylbenz-[α]-anthracene (DMBA)-Induced Breast …

JP Rojas-Armas, JL Arroyo-Acevedo… - Molecules, 2020 - mdpi.com
C. citratus essential oil and carvacrol have shown an antitumor effect on breast tumor cell
lines; the main objective of this research was to evaluate the antitumor effect of the essential …

Targeting Immunometabolism Mediated by CD73 Pathway in EGFR-Mutated Non-small Cell Lung Cancer: A New Hope for Overcoming Immune Resistance

A Passarelli, M Aieta, A Sgambato… - Frontiers in …, 2020 - frontiersin.org
Despite the relevant antitumor efficacy of immunotherapy in advanced non-small cell lung
cancer (NSCLC), the results in patients whose cancer harbors activating epidermal growth …