Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder whose aetiology is
still unknown. Most hypotheses point out the gut-brain axis as a key factor for IBS. The axis is …

Cancer is the second leading cause of death, and incidences are increasing globally.
Simply defined, cancer is the uncontrolled proliferation of a cell, and depending on the …

Background & Aims Mutations in the tetratricopeptide repeat domain 7A gene (TTC7A)
cause intestinal epithelial and immune defects. Patients can become immune deficient and …

Branched chain amino acids (BCAAs) are essential amino acids involved in regulation of
feed intake. The function of BCAAs on the central nervous system has been extensively …

Metabotropic glutamate receptors (mGluRs) are an essential component of the mammalian
central nervous system. These receptors modulate neuronal excitability in response to …

Schizophrenia (SZ) is a psychiatric disorder that constitutes one of the top 10 global causes
of disability. More recently, a potential pathogenic role for the gut microbial community …

Obesity is a multifactorial disease, which in turn contributes to the onset of comorbidities,
such as diabetes and atherosclerosis. Moreover, there are only few options available for …

Strategies to increase feed intake are of great importance for producing more meat in swine
production. Intestinal and hypothalamic amino acid receptors are found to largely participate …

Nutrients sensing is crucial for fundamental metabolism and physiological functions, and it is
also an essential component for maintaining body homeostasis. Traditionally, basic taste …

Cisplatin, a chemotherapeutic drug, is known for causing gastrointestinal disorders and
neuropathic pain, but its impact on visceral sensitivity is unclear. Monosodium glutamate …