Organ transplantation is the most effective therapy for patients with end-stage disease.
Preservation solutions and techniques are crucial for donor organ quality, which is directly …

Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

Ex vivo normothermic perfusion (EVNP) is a novel method of preservation that restores
circulation and allows an organ to regain function prior to transplantation. The aim of this …

Normothermic machine perfusion (NMP) technologies are emerging as an important adjunct
in organ preservation and transplantation. NMP can enable the reduction or avoidance of …

Background. Normothermic ex vivo kidney perfusion (NEVKP) has shown promising results
for preservation, assessment, and reconditioning of kidney allografts in preclinical studies …

Transportable normothermic kidney perfusion for 24 hours or longer could enable viability
assessment of marginal grafts, increased organ use, and improved transplant logistics …

Background. Normothermic perfusion is an alternative but little studied method of organ
preservation. Herein, we report the first case of ex vivo normothermic renal transplant …

Animal experimentation is necessary to characterize human diseases and design adequate
therapeutic interventions. In renal transplantation research, the limited number of in vitro …

Background. Better preservation strategies for the storage of donation after circulatory death
grafts are essential to improve graft function and to increase the kidney donor pool. We …

The increased utilization of high-risk renal grafts for transplantation requires optimization of
pretransplant organ assessment strategies. Current decision-making methods to accept an …