MicroRNAs: Potential candidates for diagnosis and treatment of colorectal cancer

A Moridikia, H Mirzaei, A Sahebkar… - Journal of cellular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is known as the third common cancer worldwide and an important
public health problem in different populations. Several genetics and environmental risk …

The impact of miRNA in colorectal cancer progression and its liver metastases

O Balacescu, D Sur, C Cainap, S Visan… - International journal of …, 2018 - mdpi.com
Colorectal cancer (CRC) is one of the most commonly diagnosed malignancies with a high
incidence and mortality rate. An essential challenge in colorectal cancer management is to …

Human adipose mesenchymal stem cell-derived exosomal-miRNAs are critical factors for inducing anti-proliferation signalling to A2780 and SKOV-3 ovarian cancer …

AMMT Reza, YJ Choi, H Yasuda, JH Kim - Scientific reports, 2016 - nature.com
An enigmatic question exists concerning the pro-or anti-cancer status of mesenchymal stem
cells (MSCs). Despite growing interest, this question remains unanswered, and the debate …

Long non-coding RNA HOTAIR knockdown enhances radiosensitivity through regulating microRNA-93/ATG12 axis in colorectal cancer

Y Liu, X Chen, X Chen, J Liu, H Gu, R Fan… - Cell Death & Disease, 2020 - nature.com
Colorectal cancer (CRC) is a global healthcare problem. Radioresistance is a huge setback
for CRC radiotherapy. In this text, the roles and molecular mechanisms of long non-coding …

MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications

AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …

MiRNA-93: a novel signature in human disorders and drug resistance

BM Hussen, SR Abdullah, MF Rasul, ZH Jawhar… - Cell Communication and …, 2023 - Springer
Abstract miRNA-93 is a member of the miR-106b-25 family and is encoded by a gene on
chromosome 7q22. 1. They play a role in the etiology of various diseases, including cancer …

[HTML][HTML] The crosstalk between microRNAs and the Wnt/β-catenin signaling pathway in cancer

Y Peng, X Zhang, X Feng, X Fan, Z Jin - Oncotarget, 2017 - ncbi.nlm.nih.gov
Mounting evidence has indicated microRNA (miR) dysregulation and the Wnt/β-catenin
signaling pathway jointly drive carcinogenesis, cancer metastasis, and drug-resistance. The …

Therapeutic strategies targeting Wnt/β‑catenin signaling for colorectal cancer

Y Ji, J Lv, D Sun, Y Huang - … journal of molecular …, 2022 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …

microRNA regulation of Wnt signaling pathways in development and disease

JL Song, P Nigam, SS Tektas, E Selva - Cellular signalling, 2015 - Elsevier
Wnt signaling pathways and microRNAs (miRNAs) are critical regulators of development.
Aberrant Wnt signaling pathways and miRNA levels lead to developmental defects and …

Role of Wnt/β‐catenin signaling regulatory microRNAs in the pathogenesis of colorectal cancer

F Rahmani, A Avan, SI Hashemy… - Journal of cellular …, 2018 - Wiley Online Library
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. In more
than 90% of all CRC patients, the master oncogenic Ras‐Wnt signaling axis is over …