Exploring novel therapeutic targets in the common pathogenic factors in migraine and neuropathic pain

J Tajti, D Szok, A Csáti, Á Szabó, M Tanaka… - International Journal of …, 2023 - mdpi.com
Migraine and neuropathic pain (NP) are both painful, disabling, chronic conditions which
exhibit some symptom similarities and are thus considered to share a common etiology. The …

Botulinum toxin in movement disorders: an update

C Anandan, J Jankovic - Toxins, 2021 - mdpi.com
Since its initial approval in 1989 by the US Food and Drug Administration for the treatment of
blepharospasm and other facial spasms, botulinum toxin (BoNT) has evolved into a …

Efficacy and safety of botulinum toxin type A on persistent myofascial pain: A randomized clinical trial

G De la Torre Canales, N Alvarez-Pinzon… - Toxins, 2020 - mdpi.com
This study assessed the safety and efficacy of three different doses of BoNT-A for persistent
myofascial pain (MFP). One hundred female subjects were randomly assigned into five …

Botulinum toxin-A effects on pain, somatosensory and psychosocial features of patients with refractory masticatory myofascial pain: a randomized double-blind clinical …

G De la Torre Canales, RL Poluha, LR Bonjardim… - Scientific Reports, 2024 - nature.com
The antinociceptive effect of BoNT-A have been well documented in animal studies;
however, results of few but well-designed randomized placebo-controlled clinical trials …

Neurotoxins acting at synaptic sites: A brief review on mechanisms and clinical applications

K Zhou, W Luo, T Liu, Y Ni, Z Qin - Toxins, 2022 - mdpi.com
Neurotoxins generally inhibit or promote the release of neurotransmitters or bind to
receptors that are located in the pre-or post-synaptic membranes, thereby affecting …

Botulinum toxin A in postherpetic neuralgia: a parallel, randomized, double-blind, single-dose, placebo-controlled trial

Z Apalla, E Sotiriou, A Lallas, E Lazaridou… - The Clinical journal …, 2013 - journals.lww.com
Objectives: Cumulative evidence support a beneficial effect of botulinum toxin A (BTX-A) in
postherpetic neuralgia (PHN). We aimed to assess efficacy, safety, and tolerability of BTX-A …

Long-term effects of a single application of botulinum toxin type A in temporomandibular myofascial pain patients: A controlled clinical trial

G De la Torre Canales, MB Câmara-Souza, RL Poluha… - Toxins, 2022 - mdpi.com
This study assessed the long-term effects of botulinum toxin type A (BoNT-A) in subjective
pain, pain sensibility, and muscle thickness in persistent myofascial temporomandibular …

Treatment of localized and referred masticatory myofascial pain with botulinum toxin injection

JF Montes-Carmona, LM Gonzalez-Perez… - Toxins, 2020 - mdpi.com
Botulinum toxin type A (BTA) injection is considered an available alternative treatment for
myofascial pain. However, its efficacy in treating masticatory myofascial pain syndrome …

Chronic facial pain: Trigeminal neuralgia, persistent idiopathic facial pain, and myofascial pain syndrome—an evidence-based narrative review and etiological …

R Gerwin - International journal of environmental research and …, 2020 - mdpi.com
Trigeminal neuralgia (TN), the most common form of severe facial pain, may be confused
with an ill-defined persistent idiopathic facial pain (PIFP). Facial pain is reviewed and a …

[HTML][HTML] A systematic review on extracorporeal shock wave therapy and botulinum toxin for spasticity treatment: a comparison on efficacy

EE Mihai, MN Popescu, AN Iliescu… - European Journal of …, 2022 - ncbi.nlm.nih.gov
CONCLUSIONS A beneficial effect on spasticity was found for both treatments: evidence
showed that ESWT and BoNT-A can ameliorate spasticity considering parameters such as …