Cardiovascular disease and COPD: dangerous liaisons?
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently occur together and their coexistence is associated with worse outcomes than …
frequently occur together and their coexistence is associated with worse outcomes than …
Comorbidities of COPD
A Cavaillès, G Brinchault-Rabin… - European …, 2013 - Eur Respiratory Soc
By 2020, chronic obstructive pulmonary disease (COPD) will be the third cause of mortality.
Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco …
Extrapulmonary comorbidities influence the prognosis of patients with COPD. Tobacco …
Analysis of chronic obstructive pulmonary disease exacerbations with the dual bronchodilator QVA149 compared with glycopyrronium and tiotropium (SPARK): a …
JA Wedzicha, M Decramer, JH Ficker… - The lancet Respiratory …, 2013 - thelancet.com
Background We evaluated the effect of dual, longacting inhaled bronchodilator treatment on
exacerbations in patients with severe and very severe chronic obstructive pulmonary …
exacerbations in patients with severe and very severe chronic obstructive pulmonary …
Adaptive designs for clinical trials
Adaptive Designs for Clinical Trials | New England Journal of Medicine Skip to main content The
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
New England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES …
Pharmacology and therapeutics of bronchodilators
M Cazzola, CP Page, L Calzetta, MG Matera - Pharmacological Reviews, 2012 - ASPET
Bronchodilators are central in the treatment of of airways disorders. They are the mainstay of
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …
the current management of chronic obstructive pulmonary disease (COPD) and are critical in …
The Adaptive designs CONSORT Extension (ACE) statement: a checklist with explanation and elaboration guideline for reporting randomised trials that use an …
Adaptive designs (ADs) allow pre-planned changes to an ongoing trial without
compromising the validity of conclusions and it is essential to distinguish pre-planned from …
compromising the validity of conclusions and it is essential to distinguish pre-planned from …
Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study
ML Decramer, KR Chapman, R Dahl, P Frith… - The lancet Respiratory …, 2013 - thelancet.com
Background We compared the efficacy and safety of indacaterol and tiotropium in patients
with severe chronic obstructive pulmonary disease (COPD) and a history of at least one …
with severe chronic obstructive pulmonary disease (COPD) and a history of at least one …
Leitlinie zur Diagnostik und Therapie von Patienten mit chronisch obstruktiver Bronchitis und Lungenemphysem (COPD)
C Vogelmeier, R Buhl, O Burghuber, CP Criée… - …, 2018 - thieme-connect.com
Das vorliegende Dokument ist eine Neufassung und Aktualisierung der Leitlinie zur
Diagnostik und Therapie von Patienten mit COPD, die die bisherige Version aus dem Jahr …
Diagnostik und Therapie von Patienten mit COPD, die die bisherige Version aus dem Jahr …
Twenty‐five years of confirmatory adaptive designs: opportunities and pitfalls
'Multistage testing with adaptive designs' was the title of an article by Peter Bauer that
appeared 1989 in the German journal Biometrie und Informatik in Medizin und Biologie. The …
appeared 1989 in the German journal Biometrie und Informatik in Medizin und Biologie. The …
Dual combination therapy versus long‐acting bronchodilators alone for chronic obstructive pulmonary disease (COPD): a systematic review and network meta …
Background Long‐acting bronchodilators such as long‐acting β‐agonist (LABA), long‐
acting muscarinic antagonist (LAMA), and LABA/inhaled corticosteroid (ICS) combinations …
acting muscarinic antagonist (LAMA), and LABA/inhaled corticosteroid (ICS) combinations …