What have the mechanisms of resistance to glyphosate taught us?

DL Shaner, RB Lindenmeyer… - Pest management …, 2012 - Wiley Online Library
The intensive use of glyphosate alone to manage weeds has selected populations that are
glyphosate resistant. The three mechanisms of glyphosate resistance that have been …

Biosynthesis of the aromatic amino acids

J Pittard, J Yang - EcoSal Plus, 2008 - Am Soc Microbiol
This chapter describes in detail the genes and proteins of Escherichia coli involved in the
biosynthesis and transport of the three aromatic amino acids tyrosine, phenylalanine, and …

A Novel P106L Mutation in EPSPS and an Unknown Mechanism(s) Act Additively To Confer Resistance to Glyphosate in a South African Lolium rigidum Population

SS Kaundun, RP Dale, IA Zelaya, G Dinelli… - Journal of Agricultural …, 2011 - ACS Publications
Glyphosate resistance evolution in weeds is a growing problem in world agriculture. Here,
we have investigated the mechanism (s) of glyphosate resistance in a Lolium rigidum …

[HTML][HTML] A new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) …

S Eschenburg, W Kabsch, ML Healy… - Journal of Biological …, 2003 - ASBMB
UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-
phosphate synthase (AroA) constitute the small enzyme family of enolpyruvyl transferases …

Targeting shikimate pathway: In silico analysis of phosphoenolpyruvate derivatives as inhibitors of EPSP synthase and DAHP synthase

MD de Oliveira, JO Araujo, JMP Galúcio… - Journal of Molecular …, 2020 - Elsevier
The shikimate pathway consists of seven enzymatic steps involved in the conversion of
erythrose-4-phosphate and phosphoenolpyruvate to chorismate and also responsible to the …

Construction and assessment of reaction models of class I EPSP synthase: molecular docking and density functional theoretical calculations

TC Ramalho, MS Caetano, EFF da Cunha… - Journal of …, 2009 - Taylor & Francis
The high frequency of contamination by herbicides suggests the need for more active and
selective herbicides. Glyphosate is the active component of one of the top-selling herbicides …

Sustainability and stewardship of glyphosate and glyphosate-resistant crops

RD Sammons, DC Heering, N Dinicola, H Glick… - Weed …, 2007 - cambridge.org
The significance of glyphosate and the appearance of glyphosate-resistant weeds have
raised concerns about glyphosate sustainability. Resistance-prevention strategies, however …

EPSPS Gene Amplification in Glyphosate-Resistant Italian Ryegrass (Lolium perenne ssp. multiflorum) Populations from Arkansas (United States)

RA Salas, RC Scott, FE Dayan… - Journal of agricultural …, 2015 - ACS Publications
Glyphosate-resistant Italian ryegrass was detected in Arkansas (United States) in 2007. In
2014, 45 populations were confirmed resistant in eight counties across the state. The level of …

UDP-N-acetylmuramic Acid (UDP-MurNAc) Is a Potent Inhibitor of MurA (Enolpyruvyl-UDP-GlcNAc Synthase)

S Mizyed, A Oddone, B Byczynski, DW Hughes… - Biochemistry, 2005 - ACS Publications
Purified recombinant MurA (enolpyruvyl-UDP-GlcNAc synthase) overexpressed in
Escherichia coli had significant amounts of UDP-MurNAc (UDP-N-acetylmuramic acid) …

Isolation from Ochrobactrum anthropi of a Novel Class II 5-Enopyruvylshikimate-3-Phosphate Synthase with High Tolerance to Glyphosate

YS Tian, AS Xiong, J Xu, W Zhao, F Gao… - Applied and …, 2010 - Am Soc Microbiol
Applying the genomic library construction process and colony screening, a novel aro A gene
encoding 5-enopyruvylshikimate-3-phosphate synthase from Ochrobactrum anthropi was …