The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta-analysis

N Houssami, P Macaskill, M Luke Marinovich… - Annals of surgical …, 2014 - Springer
Purpose There is no consensus on what constitutes adequate negative margins in breast-
conserving therapy (BCT). We systematically review the evidence on surgical margins in …

A randomized, controlled trial of cavity shave margins in breast cancer

AB Chagpar, BK Killelea, TN Tsangaris… - … England Journal of …, 2015 - Mass Medical Soc
Background Routine resection of cavity shave margins (additional tissue circumferentially
around the cavity left by partial mastectomy) may reduce the rates of positive margins …

Preoperative localization and surgical margins in conservative breast surgery

F Corsi, L Sorrentino, D Bossi… - … journal of surgical …, 2013 - Wiley Online Library
Breast‐conserving surgery (BCS) is the treatment of choice for early breast cancer. The
adequacy of surgical margins (SM) is a crucial issue for adjusting the volume of excision and …

Definition and management of positive margins for invasive breast cancer

A Nayyar, KK Gallagher, KP McGuire - Surgical Clinics, 2018 - surgical.theclinics.com
From the Halsted radical mastectomy to transcriptomics-based personalized therapy, the
management of breast cancer has witnessed a massive evolution in the past 5 decades. The …

Resection of cavity shave margins in stage 0–III breast cancer patients undergoing breast conserving surgery: a prospective multicenter randomized controlled trial

E Dupont, T Tsangaris, C Garcia-Cantu… - 2021 - journals.lww.com
Objective: Single-center studies have demonstrated that resection of cavity shave margins
(CSM) halves the rate of positive margins and re-excision in breast cancer patients …

Impact of routine cavity shave margins on breast cancer re-excision rates

A Kobbermann, A Unzeitig, XJ Xie, J Yan… - Annals of surgical …, 2011 - Springer
Purpose Breast-conserving therapy (BCT) is an accepted method of treating early breast
cancer. We hypothesized that routine excision of additional cavity shave margins (CSM) at …

The effects of additional tumor cavity sampling at the time of breast-conserving surgery on final margin status, volume of resection, and pathologist workload

M Rizzo, R Iyengar, SGA Gabram, J Park… - Annals of Surgical …, 2010 - Springer
Introduction Margin status is an important prognostic factor for local recurrence after breast-
conserving surgery (BCS) in patients with breast malignancy. It is unclear whether the …

Cavity shaving plus lumpectomy versus lumpectomy alone for patients with breast cancer undergoing breast-conserving surgery: a systematic review and meta …

K Wang, Y Ren, J He - PLoS One, 2017 - journals.plos.org
The margin status is a well-established prognostic predictor for patients undergoing breast-
conserving surgery (BCS). Recent data suggested that cavity shaving in addition to …

Margins in breast conservation: a clinician's perspective and what the literature tells us

N Houssami, M Morrow - Journal of surgical oncology, 2014 - Wiley Online Library
The optimal margin in breast‐conserving surgery is controversial, and re‐excision is
common. Pathologic margin assessment is not standardized, and tumor biology and the use …

Volume of excision and cosmesis with routine cavity shave margins technique

J Mook, R Klein, A Kobbermann, A Unzeitig… - Annals of surgical …, 2012 - Springer
Background Cavity shave margin (CSM) removal is a surgical technique that reduces re-
excision rates. One criticism of this technique has been that negative margins are obtained …