An interoceptive homeostatic system monitors levels of CO2/H+ and provides a
proportionate drive to respiratory control networks that adjust lung ventilation to maintain …

Autonomic dysfunction is implicated from clinical, neuroimaging and experimental studies in
sudden and unexpected death in epilepsy (SUDEP). Neuropathological analysis in SUDEP …

Current models of respiratory CO2 chemosensitivity are centred around the function of a
specific population of neurons residing in the medullary retrotrapezoid nucleus (RTN) …

Communication between astrocytes and neurons has a profound effect on the
pathophysiology of Alzheimer's disease (AD). Astrocytes regulate homeostasis and increase …

µ-Opioid receptors (MORs) are responsible for mediating both the analgesic and respiratory
effects of opioid drugs. By binding to MORs in brainstem regions involved in controlling …

New Findings What is the central question of this study? What is the relationship between
neuroanatomical and functional respiratory changes in an experimental model of …

This study was conducted with aim of investigating the consequences of sleep deprivation
(SD) on cognitive functions. For this purpose, adult male rats were subjected to SD protocol …

Astrocyte activation in the spinal dorsal horn may play an important role in the development
of chronic neuropathic pain, but the mechanisms involved in astrocyte activation and their …

Breathing is regulated by a host of arousal and sleep-wake state-dependent
neuromodulators to maintain respiratory homeostasis. Modulators such as acetylcholine …

Astrocyte heterogeneity is an emerging concept in which astrocytes within or between brain
regions show variable morphological and/or gene expression profiles that presumably …