Implication of SARS-CoV-2 immune escape spike variants on secondary and vaccine breakthrough infections

L Ahmad - Frontiers in immunology, 2021 - frontiersin.org
COVID-19 pandemic remains an on-going global health and economic threat that has
amassed millions of deaths. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV …

Artificial intelligence in surveillance, diagnosis, drug discovery and vaccine development against COVID-19

G Arora, J Joshi, RS Mandal, N Shrivastava, R Virmani… - Pathogens, 2021 - mdpi.com
As of August 6th, 2021, the World Health Organization has notified 200.8 million laboratory-
confirmed infections and 4.26 million deaths from COVID-19, making it the worst pandemic …

Covid-19 breakthrough infections in vaccinated health care workers

M Bergwerk, T Gonen, Y Lustig, S Amit… - … England Journal of …, 2021 - Mass Medical Soc
Background Despite the high efficacy of the BNT162b2 messenger RNA vaccine against
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), rare breakthrough …

Clinical characterization and genomic analysis of samples from COVID-19 breakthrough infections during the second wave among the various states of India

N Gupta, H Kaur, PD Yadav, L Mukhopadhyay… - Viruses, 2021 - mdpi.com
From March to June 2021, India experienced a deadly second wave of COVID-19, with an
increased number of post-vaccination breakthrough infections reported across the country …

Reported adverse effects and attitudes among Arab populations following COVID-19 vaccination: a large-scale multinational study implementing machine learning …

MM Hatmal, MAI Al-Hatamleh, AN Olaimat… - Vaccines, 2022 - mdpi.com
Background: The unprecedented global spread of coronavirus disease 2019 (COVID-19)
has imposed huge challenges on the healthcare facilities, and impacted every aspect of life …

SARS-CoV-2 E484K mutation narrative review: epidemiology, immune escape, clinical implications, and future considerations

WT Yang, WH Huang, TL Liao, TH Hsiao… - Infection and Drug …, 2022 - Taylor & Francis
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spread rapidly over the
world and claimed million lives. The virus evolves constantly, and a swarm of mutants is a …

Immune profile and clinical outcome of breakthrough cases after vaccination with an inactivated SARS-CoV-2 vaccine

LF Duarte, NMS Gálvez, C Iturriaga… - Frontiers in …, 2021 - frontiersin.org
Constant efforts to prevent infections by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are actively carried out around the world. Several vaccines are currently …

Theaflavin 3-gallate inhibits the main protease (Mpro) of SARS-CoV-2 and reduces its count in vitro

M Chauhan, VK Bhardwaj, A Kumar, V Kumar… - Scientific Reports, 2022 - nature.com
The main protease (Mpro) of SARS-CoV-2 has been recognized as an attractive drug target
because of its central role in viral replication. Our previous preliminary molecular docking …

Breakthrough COVID-19 infections among health care workers after two doses of ChAdOx1 nCoV-19 vaccine

VKM Niyas, R Arjun - QJM: An International Journal of Medicine, 2021 - academic.oup.com
The ChAdOx1 nCoV-19 vaccine (University of Oxford, AstraZeneca and the Serum Institute
of India) and the BBV152 vaccine (Bharath Biotech and Indian Council of Medical Research) …

Breakthrough SARS-CoV-2 infections after COVID-19 immunization

J Hirsh, T Htay, S Bhalla, V Nguyen… - Journal of …, 2022 - journals.sagepub.com
As no vaccines are 100% effective at preventing illness, COVID-19 vaccine breakthrough
cases are expected. We here aim to review the most recent literature on COVID-19 vaccine …