The continuous exchange of chemicals with blood and the non-invasive collection make
saliva an interesting specimen for clinical applications, from the detection of biomarkers to …

Saliva is secreted from the salivary glands and has multiple functions, including mouth
cleaning and protection, antibacterial effects and digestion. With the rapid advancement in …

Salivary bioscience technologies such as electrophoresis are widely applied for diagnosing
systemic health status. Diagnosis using a saliva sample has emerged as a preferred …

Cancer, a local disease at an early stage, systemically evolves as it progresses by triggering
alterations in surrounding microenvironment, disturbing immune surveillance and further …

The oral squamous cell carcinoma (OSCC) 5 year survival rate of 41% has marginally
improved in the last few years, with less than a 1% improvement per year from 2005 to 2017 …

The prognosis of patients with oral squamous carcinoma (OSCC) largely depends on the
stage at diagnosis, the 5-year survival rate being approximately 30% for advanced tumors …

Fast, economic, and noninvasive, molecular analysis of saliva has the potential to become a
diagnostic tool of reference for several local and systemic diseases, oral cancer included …

Interleukin (IL)-4 and IL-13 are known as pleiotropic Th2 cytokines with a wide range of
biological properties and functions especially in immune responses. In addition, increasing …

Oral cancers are among the common head and neck malignancies. Different anticancer
therapy modalities such as chemotherapy, immunotherapy, radiation therapy, and also …

Background Oral cancer (OC) is usually diagnosed at advanced clinical stages due to its
asymptomatic nature and absence of pathognomonic signs in its early development phase …