Host defence peptides (HDPs) are short, cationic amphipathic peptides with diverse
sequences that are produced by various cells and tissues in all complex life forms. HDPs …

Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …

Defensins are a major family of host defense peptides expressed predominantly in
neutrophils and epithelial cells. Their broad antimicrobial activities and multifaceted …

Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many
organisms. Although AMPs have been essentially studied and developed as potential …

As the key components of innate immunity, human host defense antimicrobial peptides and
proteins (AMPs) play a critical role in warding off invading microbial pathogens. In addition …

Many new therapies are currently being used to treat cancer. Among these new methods,
chemotherapy based on peptides has been of great interest due to the unique advantages …

The proteins secreted by various cells (the secretomes) are a potential rich source of
biomarkers as they reflect various states of the cells at real time and at given conditions. To …

Small cationic peptides highly conserved in vertebrates, both α-and β-defensins were
primarily identified as anti-microbial compounds involved in innate immunity. While human α …

Human defensins, which are small cationic peptides produced by neutrophils and epithelial
cells, form two genetically distinct alpha and beta subfamilies. They are involved in innate …

Three‐dimensional (3D) cancer models are overlooking the scientific landscape with the
primary goal of bridging the gaps between two‐dimensional (2D) cell lines, animal models …