Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

ECMO for severe ARDS: systematic review and individual patient data meta-analysis

A Combes, GJ Peek, D Hajage, P Hardy… - Intensive care …, 2020 - Springer
Purpose To assess the effect of venovenous extracorporeal membrane oxygenation (ECMO)
compared to conventional management in patients with severe acute respiratory distress …

Clinical characteristics and day-90 outcomes of 4244 critically ill adults with COVID-19: a prospective cohort study

Intensive care medicine, 2021 - Springer
Purpose To describe acute respiratory distress syndrome (ARDS) severity, ventilation
management, and the outcomes of ICU patients with laboratory-confirmed COVID-19 and to …

Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study

M Schmidt, D Hajage, G Lebreton, A Monsel… - The Lancet …, 2020 - thelancet.com
Background Patients with COVID-19 who develop severe acute respiratory distress
syndrome (ARDS) can have symptoms that rapidly evolve to profound hypoxaemia and …

Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in Greater Paris, France: a multicentre cohort …

G Lebreton, M Schmidt, M Ponnaiah… - The Lancet …, 2021 - thelancet.com
Background In the Île-de-France region (henceforth termed Greater Paris), extracorporeal
membrane oxygenation (ECMO) for severe acute respiratory distress syndrome (ARDS) was …

Time-varying intensity of mechanical ventilation and mortality in patients with acute respiratory failure: a registry-based, prospective cohort study

M Urner, P Jüni, B Hansen, MS Wettstein… - The Lancet …, 2020 - thelancet.com
Background Mortality in acute respiratory failure remains high despite the use of lung-
protective ventilation. Recent studies have shown an association between baseline …

Static and dynamic contributors to ventilator-induced lung injury in clinical practice. Pressure, energy, and power

JJ Marini, PRM Rocco, L Gattinoni - American journal of respiratory …, 2020 - atsjournals.org
Ventilation is inherently a dynamic process. The present-day clinical practice of
concentrating on the static inflation characteristics of the individual tidal cycle (plateau …

Association between preadmission metformin use and outcomes in intensive care unit patients with sepsis and type 2 diabetes: a cohort study

Q Yang, J Zheng, W Chen, X Chen, D Wen… - Frontiers in …, 2021 - frontiersin.org
Background: Sepsis is a deadly disease worldwide. Effective treatment strategy of sepsis
remains limited. There still was a controversial about association between preadmission …

Bedside calculation of mechanical power during volume-and pressure-controlled mechanical ventilation

D Chiumello, M Gotti, M Guanziroli, P Formenti… - Critical care, 2020 - Springer
Background Mechanical power (MP) is the energy delivered to the respiratory system over
time during mechanical ventilation. Our aim was to compare the currently available methods …

Mechanical power during general anesthesia and postoperative respiratory failure: a multicenter retrospective cohort study

P Santer, LJ Wachtendorf, A Suleiman, TT Houle… - …, 2022 - pubs.asahq.org
Background Mechanical power during ventilation estimates the energy delivered to the
respiratory system through integrating inspiratory pressures, tidal volume, and respiratory …