Metabolic labeling of glycerophospholipids via clickable analogs derivatized at the lipid headgroup

CF Ancajas, TJ Ricks, MD Best - Chemistry and physics of lipids, 2020 - Elsevier
Metabolic labeling, in which substrate analogs containing diminutive tags can infiltrate
biosynthetic pathways and generate labeled products in cells, has led to dramatic …

Chemical probes for tagging mycobacterial lipids

KJ Biegas, BM Swarts - Current Opinion in Chemical Biology, 2021 - Elsevier
Mycobacteria, which cause tuberculosis and related diseases, possess a diverse set of
complex envelope lipids that provide remarkable tolerance to antibiotics and are major …

Azido inositol probes enable metabolic labeling of inositol-containing glycans and reveal an inositol importer in mycobacteria

H Hodges, K Obeng, C Avanzi, AP Ausmus… - ACS chemical …, 2023 - ACS Publications
Bacteria from the genus Mycobacterium include pathogens that cause serious diseases in
humans and remain as difficult infectious agents to treat. Central to these challenges are the …

Design and synthesis of 4-azido-phosphatidylinositol as a potential probe for metabolic engineering of glycosylphosphatidylinositol on cells

KC Craig, Z Guo - Journal of carbohydrate chemistry, 2022 - Taylor & Francis
A diacyl phosphatidylinositol (PI) derivative with an azide linked to its inositol C4-position
was effectively synthesized in 19 steps for the longest linear sequence and in a ca. 1 …

Stereoselective synthesis of novel bis-homoinositols with bicyclo [4.2. 0] octane motifs

AZ Barotcu, A Karanfil, E Şahin, L Kelebekli - Carbohydrate Research, 2022 - Elsevier
Starting from cyclooctatetraene, bis-homoconduritols with cis-inositol and allo-inositol (or
bicyclo [4.2. 0] octane motif) structures were synthesized. Photooxygenation of trans-7, 8 …

[HTML][HTML] Chemical Synthesis of 6-Azido-6-Deoxy Derivatives of Phosphatidylinositol Containing Different Fatty Acid Chains

MR Molla, P Gupta, R Rohokale, Z Guo - Molecules, 2024 - mdpi.com
This paper describes the synthesis of two 6-azido-6-deoxy derivatives of
phosphatidylinositol (PI), which contained different fatty acid chains. These syntheses …

Access to Enantiomeric Organic Compounds with Potential for Synthesis via Racemic Conglomerates: Inositol Derivatives as a Case in Point

NT Patil, MT Patil, N Sarkar, RG Gonnade… - Crystal Growth & …, 2021 - ACS Publications
The crystal structure database was used to identify inositol derivatives that could be
crystallizing as racemic conglomerates. Among the six racemic inositol derivatives identified …

Clickable Lipid Precursors as Chemical Tools for Imaging and Tracking Lipids

CAF Ancajas - 2023 - trace.tennessee.edu
The regulation of lipid metabolism is crucial for maintaining the human body, as disruptions
in lipid homeostasis have drastic implications. While lipids are known for their roles as …

Ferrier-Carbocyclisierung

JJ Li - … : Eine Sammlung von detaillierten Mechanismen und …, 2024 - Springer
Dieser Prozess hat sich als von erheblichem Wert für die effiziente, einstufige Umwandlung
von 5, 6-ungesättigten Hexopyranose-Derivaten in funktionalisierte Cyclohexanone …

Stereoselective Synthesis of Novel Bis-Homoinositols with Bicyclo [4.2. 0] Octane Motifs

L Kelebekli, AZ Barotcu, A Karanfil, E Şahin - Available at SSRN 4092181 - papers.ssrn.com
Starting from cyclooctatetraene, bis-homochonduritols with cis-inositol and allo-inositol (or
bicyclo [4.2. 0] octane motif) structures were synthesized. Photooxygenation of trans-7, 8 …