Cell-mediated immunity and the outcome of hepatitis C virus infection
NH Shoukry, AG Cawthon, CM Walker - Annu. Rev. Microbiol., 2004 - annualreviews.org
▪ Abstract The hepatitis C virus (HCV) infects approximately three percent of the world's
population. Some individuals resolve the infection spontaneously, but the majority develop …
population. Some individuals resolve the infection spontaneously, but the majority develop …
Evasion of innate and adaptive immunity by flaviviruses
MS Diamond - Immunology and cell biology, 2003 - Wiley Online Library
After a virus infects an animal, antiviral responses are generated that attempt to prevent
dissemination. Interferons, antibody, complement, T and natural killer cells all contribute to …
dissemination. Interferons, antibody, complement, T and natural killer cells all contribute to …
Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies: African trypanosomes as paradigm
B Stijlemans, K Conrath, V Cortez-Retamozo… - Journal of Biological …, 2004 - ASBMB
Antigen variation is a successful defense system adopted by several infectious agents to
evade the host immune response. The principle of this defense strategy in the African …
evade the host immune response. The principle of this defense strategy in the African …
Molecular and functional analyses of Kunjin virus infectious cDNA clones demonstrate the essential roles for NS2A in virus assembly and for a nonconservative …
WJ Liu, HB Chen, AA Khromykh - Journal of virology, 2003 - Am Soc Microbiol
ABSTRACT A number of full-length cDNA clones of Kunjin virus (KUN) were previously
prepared; it was shown that two of them, pAKUN and FLSDX, differed in specific infectivities …
prepared; it was shown that two of them, pAKUN and FLSDX, differed in specific infectivities …
Efficient error correction for next-generation sequencing of viral amplicons
Background Next-generation sequencing allows the analysis of an unprecedented number
of viral sequence variants from infected patients, presenting a novel opportunity for …
of viral sequence variants from infected patients, presenting a novel opportunity for …
Next-generation sequencing reveals large connected networks of intra-host HCV variants
Background Next-generation sequencing (NGS) allows for sampling numerous viral variants
from infected patients. This provides a novel opportunity to represent and study the …
from infected patients. This provides a novel opportunity to represent and study the …
[HTML][HTML] Exposure to low infective doses of HCV induces cellular immune responses without consistently detectable viremia or seroconversion in chimpanzees
MT Shata, N Tricoche, M Perkus, D Tom, B Brotman… - Virology, 2003 - Elsevier
In hepatitis C virus (HCV) infection, there is accumulating data suggesting the presence of
cellular immune responses to HCV in exposed but seemingly uninfected populations. Some …
cellular immune responses to HCV in exposed but seemingly uninfected populations. Some …
Divergence and recombination of clinical herpes simplex virus type 2 isolates
P Norberg, MJ Kasubi, L Haarr, T Bergström… - Journal of …, 2007 - Am Soc Microbiol
Herpes simplex virus type 2 (HSV-2) infects the genital mucosa and is one of the most
common sexually transmitted viruses. Here we sequenced a segment comprising 3.5% of …
common sexually transmitted viruses. Here we sequenced a segment comprising 3.5% of …
Hepatitis C virus NS3 ATPases/helicases from different genotypes exhibit variations in enzymatic properties
The NS3 ATPase/helicase was isolated and characterized from three different infectious
clones of hepatitis C virus (HCV). One helicase was from a genotype that normally responds …
clones of hepatitis C virus (HCV). One helicase was from a genotype that normally responds …
Modulation of the peripheral T-Cell response by CD4 mutants of hepatitis C virus: transition from a Th1 to a Th2 response
JH Wang, TJ Layden, DD Eckels - Human immunology, 2003 - Elsevier
A disturbing feature of hepatitis C virus (HCV) is its long-term persistence in roughly 85% of
those infected. Escape mutants may play a major role in HCV persistence. Our previous …
those infected. Escape mutants may play a major role in HCV persistence. Our previous …