Three important factors, including genetics, environment factors and autoimmunity play a
role in the pathogenesis of rheumatoid arthritis (RA). The heritability of RA has been …

In recent years, diagnostic and therapeutic approaches for rheumatoid arthritis (RA) have
continued to improve. However, in the advanced stages of the disease, patients are unable …

Background It has comprehensively been acknowledged that a genetic contribution,
especially in immune inflammatory players, such as interleukin (IL)-6 and tumor necrosis …

The footprint of cytokines is evident in almost every biological process, such as
development, as well as the pathogenesis of the different diseases, immune responses to …

Glucose is the most important source of energy and homeostasis. Recent investigations are
clarifying that glucose metabolism might be altered in rheumatoid arthritis (RA), which would …

Immune system CD4 T-cells with high cell-surface CD26 expression show anti-tumoral
properties. When engineered with a chimeric antigen receptor (CAR), they incite strong …

Background Rheumatoid arthritis (RA) is an autoinflammatory disease, in which synovial
cells in the joints produce a complex network of cytokines. Vascular endothelial growth …

Background: Emerging evidence suggests that secretome of mesenchymal stem cells has
many anti-inflammatory and regenerative properties, which makes it a suitable candidate for …

Background: It is reported that DPP4 is associated with bone metabolism, osteoporosis and
other orthopedic diseases, but the correlation between DPP4 and osteonecrosis of the …

Background: Dipeptidyl Peptidase IV (DPP4/CD26) and Amino Peptidase N (APN/CD13)
have essential roles in inflammatory diseases. The current study aimed to determine …