Volumetric MRI findings in mild traumatic brain injury (mTBI) and neuropsychological outcome

ED Bigler - Neuropsychology Review, 2023 - Springer
Region of interest (ROI) volumetric assessment has become a standard technique in
quantitative neuroimaging. ROI volume is thought to represent a coarse proxy for making …

Mechanical properties of the cranial meninges: a systematic review

DR Walsh, Z Zhou, X Li, J Kearns… - Journal of …, 2021 - liebertpub.com
The meninges are membranous tissues that are pivotal in maintaining homeostasis of the
central nervous system. Despite the importance of the cranial meninges in nervous system …

A common neural signature of brain injury in concussion and subconcussion

AA Hirad, JJ Bazarian, K Merchant-Borna… - Science …, 2019 - science.org
The midbrain is biomechanically susceptible to force loading from repetitive subconcussive
head impacts (RSHI), is a site of tauopathy in chronic traumatic encephalopathy (CTE), and …

[HTML][HTML] Convolutional neural network for efficient estimation of regional brain strains

S Wu, W Zhao, K Ghazi, S Ji - Scientific reports, 2019 - nature.com
Head injury models are important tools to study concussion biomechanics but are
impractical for real-world use because they are too slow. Here, we develop a convolutional …

Mechanisms and variances of rotation-induced brain injury: a parametric investigation between head kinematics and brain strain

K Bian, H Mao - Biomechanics and modeling in mechanobiology, 2020 - Springer
There lacks a comprehensive understanding of the correlation between head kinematics
and brain strain especially deep-brain strain, partially resulting the deficiency of …

Mechanical characterisation of the human dura mater, falx cerebri and superior sagittal sinus

DR Walsh, AM Ross, DT Newport, Z Zhou, J Kearns… - Acta biomaterialia, 2021 - Elsevier
The cranial meninges have been shown to play a pivotal role in traumatic brain injury
mechanopathology. However, while the mechanical response of the brain and its many …

[HTML][HTML] A quantitative relationship between rotational head kinematics and brain tissue strain from a 2-D parametric finite element analysis

RW Carlsen, AL Fawzi, Y Wan, H Kesari, C Franck - Brain Multiphysics, 2021 - Elsevier
Given the complex nature of traumatic brain injury (TBI), assessment of injury risk directly
from kinematic measures of head motion remains a challenge. Despite this challenge …

Translational models of mild traumatic brain injury tissue biomechanics

X Zhan, A Oeur, Y Liu, MM Zeineh, GA Grant… - Current Opinion in …, 2022 - Elsevier
Traumatic brain injury (TBI) is a global health concern. Mild TBI (mTBI) which accounts for
the majority of TBI cases, is hard to detect since often the imaging is normal but can still …

Predictive factors of kinematics in traumatic brain injury from head impacts based on statistical interpretation

X Zhan, Y Li, Y Liu, AG Domel, HV Alizadeh… - Annals of biomedical …, 2021 - Springer
Brain tissue deformation resulting from head impacts is primarily caused by rotation and can
lead to traumatic brain injury. To quantify brain injury risk based on measurements of …

A network-based response feature matrix as a brain injury metric

S Wu, W Zhao, B Rowson, S Rowson, S Ji - Biomechanics and modeling …, 2020 - Springer
Conventional brain injury metrics are scalars that treat the whole head/brain as a single unit
but do not characterize the distribution of brain responses. Here, we establish a network …