The bacterial membrane provides a target for antimicrobial peptides. There are two groups
of bacteria that have characteristically different surface membranes. One is the Gram …

Antimicrobial peptides (AMPs) have remarkably different structures as well as biological
activity profiles, whereupon most of these peptides are supposed to kill bacteria via …

Daptomycin is a highly efficient last-resort antibiotic that targets the bacterial cell membrane.
Despite its clinical importance, the exact mechanism by which daptomycin kills bacteria is …

The lipopeptide daptomycin is used as an antibiotic to treat severe infections with gram-
positive pathogens, such as methicillin resistant Staphylococcus aureus (MRSA) and drug …

Daptomycin is a lipopeptide antibiotic produced by the soil bacterium Streptomyces
roseosporus that is clinically used to treat severe infections with Gram-positive bacteria. In …

Despite efforts to develop new antibiotics, antibacterial resistance still develops too fast for
drug discovery to keep pace. Often, resistance against a new drug develops even before it …

Daptomycin (DAP) is a cyclic lipopeptide with in vitro activity against a variety of Gram‐
positive pathogens, including multidrug‐resistant organisms. Since its introduction into …

With the alarming increase of infections caused by pathogenic multidrug-resistant bacteria
over the last decades, antimicrobial peptides (AMPs) have been investigated as a potential …

The bactericidal, cell membrane–targeting lipopeptide antibiotic daptomycin (DAP) is an
important agent in treating invasive Staphylococcus aureus infections. However, there have …

Daptomycin is a lipopeptide antibiotic used clinically for the treatment of certain types of
Gram-positive infections, including those caused by methicillin-resistant Staphylococcus …