Nitric oxide signaling in health and disease
JO Lundberg, E Weitzberg - Cell, 2022 - cell.com
The surprising discovery that the diatomic gas nitric oxide (NO) is generated by mammalian
cells and serves to regulate a multitude of physiological processes has continued to …
cells and serves to regulate a multitude of physiological processes has continued to …
Lipolysis: cellular mechanisms for lipid mobilization from fat stores
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
acids from fat stores in adipose tissue to generate energy has experienced major revisions …
Cardiac energy metabolism in heart failure
Alterations in cardiac energy metabolism contribute to the severity of heart failure. However,
the energy metabolic changes that occur in heart failure are complex and are dependent not …
the energy metabolic changes that occur in heart failure are complex and are dependent not …
Heart failure with preserved ejection fraction: JACC scientific statement
The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …
Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases
Cardiovascular diseases (CVDs), such as ischaemic heart disease, cardiomyopathy,
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …
atherosclerosis, hypertension, stroke and heart failure, are among the leading causes of …
Cellular and molecular pathobiology of heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) affects half of all patients with heart
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …
failure worldwide, is increasing in prevalence, confers substantial morbidity and mortality …
Ceramides and other sphingolipids as drivers of cardiovascular disease
Increases in calorie consumption and sedentary lifestyles are fuelling a global pandemic of
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …
cardiometabolic diseases, including coronary artery disease, diabetes mellitus …
Sex differences in heart failure
CSP Lam, C Arnott, AL Beale… - European heart …, 2019 - academic.oup.com
The overall lifetime risk of heart failure (HF) is similar between men and women, however,
there are marked sex differences in the landscape of this condition that are both important …
there are marked sex differences in the landscape of this condition that are both important …
Obesity and heart failure with preserved ejection fraction: new insights and pathophysiological targets
BA Borlaug, MD Jensen, DW Kitzman… - Cardiovascular …, 2022 - academic.oup.com
Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …
intermingling epidemics driving perhaps the greatest unmet health problem in …
From systemic inflammation to myocardial fibrosis: the heart failure with preserved ejection fraction paradigm revisited
WJ Paulus, MR Zile - Circulation research, 2021 - Am Heart Assoc
In accordance with the comorbidity-inflammation paradigm, comorbidities and especially
metabolic comorbidities are presumed to drive development and severity of heart failure with …
metabolic comorbidities are presumed to drive development and severity of heart failure with …