Although the prevalence of malnutrition in the old age is increasing worldwide a synthetic
understanding of the impact of aging on the intake, digestion, and absorption of nutrients is …

UCHL1 is a multifunctional protein expressed at high concentrations in neurons in the brain
and spinal cord. UCHL1 plays important roles in regulating the level of cellular free ubiquitin …

Deubiquitylating enzymes (DUBs) are proteases that remove the ubiquitin moiety from
ubiquitylated substrates to antagonize the modification mediated by E3 ubiquitin ligases …

The Ubiquitin-Proteasome Pathway (UPP), which is critical for normal function in the
nervous system and is implicated in various neurological diseases, requires the small …

Abnormal cardiac fibrosis indicates cardiac dysfunction and poor prognosis in myocardial
infarction (MI) patients. Many studies have demonstrated that the ubiquitin proteasome …

Background & Aims Ubiquitination is a reversible protein modification involved in the major
cellular processes that define cell phenotype and behaviour. Ubiquitin modifications are …

Traumatic brain injury (TBI) is a major health concern. The purpose of this study is to identify
the diagnostic accuracy of ubiquitin C-terminal hydrolase-L1 (UCH-L1)—a protein biomarker …

Numerous long non-coding RNAs (lncRNAs) have been discovered as a result of advances
in sequencing methods in genomic research. Recent evidence indicates that lncRNAs may …

Traumatic brain injury (TBI) is still the leading cause of disability in young adults worldwide.
The major mechanisms–diffuse axonal injury, cerebral contusion, ischemic neurological …

The gut and the brain communicate via the nervous system, hormones, microbiota-mediated
substances, and the immune system. These intricate interactions have led to the term “gut …