Harnessing the cGAS-STING pathway to potentiate radiation therapy: current approaches and future directions
NW Colangelo, NK Gerber, RE Vatner… - Frontiers in …, 2024 - frontiersin.org
In this review, we cover the current understanding of how radiation therapy, which uses
ionizing radiation to kill cancer cells, mediates an anti-tumor immune response through the …
ionizing radiation to kill cancer cells, mediates an anti-tumor immune response through the …
DNA sensing of dendritic cells in cancer immunotherapy
W Qian, J Ye, S Xia - Frontiers in Molecular Biosciences, 2024 - frontiersin.org
Dendritic cells (DCs) are involved in the initiation and maintenance of immune responses
against malignant cells by recognizing conserved pathogen-associated molecular patterns …
against malignant cells by recognizing conserved pathogen-associated molecular patterns …
[HTML][HTML] Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies
M Danielson, CJ Nicolai, TT Vo, N Wolf, TP Burke - bioRxiv, 2024 - ncbi.nlm.nih.gov
Bacterial pathogens that invade the eukaryotic cytosol are distinctive tools for fighting
cancer, as they preferentially target tumors and can deliver cancer antigens to MHC-I …
cancer, as they preferentially target tumors and can deliver cancer antigens to MHC-I …