Stiffness and beyond: what MR elastography can tell us about brain structure and function under physiologic and pathologic conditions

Z Yin, AJ Romano, A Manduca, RL Ehman… - Topics in Magnetic …, 2018 - journals.lww.com
Brain magnetic resonance elastography (MRE) was developed on the basis of a desire to
“palpate by imaging” and is becoming a powerful tool in the investigation of …

Advanced neuroimaging role in traumatic brain injury: a narrative review

L Hu, S Yang, B Jin, C Wang - Frontiers in Neuroscience, 2022 - frontiersin.org
Traumatic brain injury (TBI) is a common source of morbidity and mortality among civilians
and military personnel. Initial routine neuroimaging plays an essential role in rapidly …

Tissue-engineered blood-brain barrier models via directed differentiation of human induced pluripotent stem cells

GN Grifno, AM Farrell, RM Linville, D Arevalo, JH Kim… - Scientific reports, 2019 - nature.com
Abstract Three-dimensional (3D) tissue-engineered models of the blood-brain barrier (BBB)
recapitulate in vivo shear stress, cylindrical geometry, and cell-ECM interactions. Here we …

Towards microstructure-informed material models for human brain tissue

S Budday, M Sarem, L Starck, G Sommer, J Pfefferle… - Acta Biomaterialia, 2020 - Elsevier
Emerging evidence suggests that the mechanical behavior of the brain plays a critical role in
development, disease, and aging. Recent studies have begun to characterize the …

Quantifying local stiffness and forces in soft biological tissues using droplet optical microcavities

G Pirnat, M Marinčič, M Ravnik… - Proceedings of the …, 2024 - National Acad Sciences
Mechanical properties of biological tissues fundamentally underlie various biological
processes and noncontact, local, and microscopic methods can provide fundamental …

Glial tissue mechanics and mechanosensing by glial cells

K Pogoda, PA Janmey - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Understanding the mechanical behavior of human brain is critical to interpret the role of
physical stimuli in both normal and pathological processes that occur in CNS tissue, such as …

Tension strain-softening and compression strain-stiffening behavior of brain white matter

F Eskandari, M Shafieian, MM Aghdam… - Annals of Biomedical …, 2021 - Springer
Brain, the most important component of the central nervous system (CNS), is a soft tissue
with a complex structure. Understanding the role of brain tissue microstructure in mechanical …

Structural anisotropy vs. mechanical anisotropy: the contribution of axonal fibers to the material properties of brain white matter

F Eskandari, M Shafieian, MM Aghdam… - Annals of biomedical …, 2021 - Springer
Brain's micro-structure plays a critical role in its macro-structure material properties. Since
the structural anisotropy in the brain white matter has been introduced due to axonal fibers …

Visco-hyperelastic characterization of human brain white matter micro-level constituents in different strain rates

M Ramzanpour, M Hosseini-Farid, J McLean… - Medical & Biological …, 2020 - Springer
In this study, we propose a computational characterization technique for obtaining the
material properties of axons and extracellular matrix (ECM) in human brain white matter. To …

Viscoelastic response of gray matter and white matter brain tissues under creep and relaxation

W Kang, L Wang, Y Fan - Journal of Biomechanics, 2024 - Elsevier
Accurate measurement of the mechanical properties of brain tissue is of paramount
importance for understanding its mechanics-biology relationship. Most published studies on …