Intermittent metabolic switching, neuroplasticity and brain health

MP Mattson, K Moehl, N Ghena… - Nature Reviews …, 2018 - nature.com
During evolution, individuals whose brains and bodies functioned well in a fasted state were
successful in acquiring food, enabling their survival and reproduction. With fasting and …

[HTML][HTML] The homeostatic force of ghrelin

S Yanagi, T Sato, K Kangawa, M Nakazato - Cell metabolism, 2018 - cell.com
Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …

Mood, food, and obesity

M Singh - Frontiers in psychology, 2014 - frontiersin.org
Food is a potent natural reward and food intake is a complex process. Reward and
gratification associated with food consumption leads to dopamine (DA) production, which in …

The Concise Guide to PHARMACOLOGY 2013/14: G protein‐coupled receptors

SPH Alexander, HE Benson… - British journal of …, 2013 - Wiley Online Library
Abstract The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of
the key properties of over 2000 human drug targets with their pharmacology, plus links to an …

From belly to brain: targeting the ghrelin receptor in appetite and food intake regulation

K Howick, BT Griffin, JF Cryan… - International journal of …, 2017 - mdpi.com
Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and
subsequent food intake. The ghrelinergic system has therefore received considerable …

Ghrelin regulates the hypothalamic-pituitary-adrenal axis and restricts anxiety after acute stress

SJ Spencer, L Xu, MA Clarke, M Lemus… - Biological …, 2012 - Elsevier
BACKGROUND: Ghrelin plays important roles in glucose metabolism, appetite, and body
weight regulation, and recent evidence suggests ghrelin prevents excessive anxiety under …

Physiological effect of ghrelin on body systems

Y Akalu, MD Molla, G Dessie… - International journal of …, 2020 - Wiley Online Library
Ghrelin is a relatively novel multifaceted hormone that has been found to exert a plethora of
physiological effects. In this review, we found/confirmed that ghrelin has effect on all body …

Common and divergent molecular mechanisms of fasting and ketogenic diets

A Paoli, GM Tinsley, MP Mattson, I De Vivo… - Trends in Endocrinology …, 2024 - cell.com
Intermittent short-term fasting (ISTF) and ketogenic diets (KDs) exert overlapping but not
identical effects on cell metabolism, function, and resilience. Whereas health benefits of KD …

Delayed gastric emptying in Parkinson's disease

S Marrinan, AV Emmanuel, DJ Burn - Movement Disorders, 2014 - Wiley Online Library
Gastrointestinal symptoms are evident in all stages of Parkinson's disease (PD). Most of the
gastrointestinal abnormalities associated with PD are attributable to impaired motility. At the …

Food for thought: reward mechanisms and hedonic overeating in obesity

PC Lee, JB Dixon - Current obesity reports, 2017 - Springer
Abstract Purpose of Review This review examines the food addiction model and the role of
food hedonic pathways in the pathogenesis and treatment of obesity. Recent Findings The …