Synthesis, in silico, and in vitro evaluation of 7-chloro-quinolines designed as myeloperoxidase inhibitors

GRC Pereira, L de Souza Fraga, RP de Jesus… - Journal of Molecular …, 2024 - Elsevier
Given the central role of the myeloperoxidase (MPO) enzyme in inflammation, MPO
inhibition is recognized as a promising pharmacological strategy for managing inflammatory …