BACKGROUND Spermatogenesis culminates in production of one of the most highly
differentiated cells in biology, the spermatozoon. The gametes that emerge from the testes …

The disintegrin and metalloprotease domain-containing protein (ADAM) family of
multidomain membrane proteins comprises at least 34 members in mammals. More than …

STUDY QUESTION Are epididymosomes implicated in protein transfer from the epididymis
to spermatozoa? SUMMARY ANSWER We characterized the contribution of epididymal …

Sperm are transcriptionally and translationally quiescent and, therefore, rely on the seminal
plasma microenvironment for function, survival and fertilization of the oocyte in the oviduct …

Among many other molecules, nitric oxide insures the correct progress of sperm capacitation
by mediating phosphorylation events. For a more comprehensive understanding of how this …

The results of artificial insemination (AI) are adversely affected by changes in sperm motility
and function throughout the cryopreservation procedure. The proteome alterations of frozen …

A combined Genotyping By Sequencing (GBS) and methylated DNA immunoprecipitation
(MeDIP) protocol was used to identify—in parallel—genetic variation (Genomic-Wide …

Hypothyroidism and thyrotoxicosis are associated with male reproductive disorders, but little
is known about the influence of the thyroid hormone milieu on seminal vesicle (SV) function …

BRI2 is a type II transmembrane protein ubiquitously expressed whose physiological
function remains poorly understood. Although several recent important advances have …

Sperm need to mature in the epididymis to become capable of fertilization. To understand
the molecular mechanisms of mouse sperm maturation, we conducted a proteomic analysis …