Autofocusing technologies for whole slide imaging and automated microscopy

Z Bian, C Guo, S Jiang, J Zhu, R Wang… - Journal of …, 2020 - Wiley Online Library
Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in
recent years. Due to the inherent tissue topography variability, accurate autofocusing …

Neural network-based processing and reconstruction of compromised biophotonic image data

MJ Fanous, P Casteleiro Costa, Ç Işıl… - Light: Science & …, 2024 - nature.com
In recent years, the integration of deep learning techniques with biophotonic setups has
opened new horizons in bioimaging. A compelling trend in this field involves deliberately …

[HTML][HTML] Self-supervised learning of hologram reconstruction using physics consistency

L Huang, H Chen, T Liu, A Ozcan - Nature Machine Intelligence, 2023 - nature.com
Existing applications of deep learning in computational imaging and microscopy mostly
depend on supervised learning, requiring large-scale, diverse and labelled training data …

Deep imaging flow cytometry

K Huang, H Matsumura, Y Zhao, M Herbig, D Yuan… - Lab on a Chip, 2022 - pubs.rsc.org
Imaging flow cytometry (IFC) has become a powerful tool for diverse biomedical applications
by virtue of its ability to image single cells in a high-throughput manner. However, there …

Identification of microplastics based on the fractal properties of their holographic fingerprint

V Bianco, D Pirone, P Memmolo, F Merola… - ACS …, 2021 - ACS Publications
Water plastic pollution is a serious problem affecting sealife, marine habitats, and the food
chain. Artificial intelligence-enabled coherent imaging has recently shown exciting …

Rapid and stain-free quantification of viral plaque via lens-free holography and deep learning

T Liu, Y Li, HC Koydemir, Y Zhang, E Yang… - Nature Biomedical …, 2023 - nature.com
A plaque assay—the gold-standard method for measuring the concentration of replication-
competent lytic virions—requires staining and usually more than 48 h of runtime. Here we …

Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy

C Li, A Moatti, X Zhang, H Troy Ghashghaei… - Biomedical Optics …, 2021 - opg.optica.org
Light-sheet fluorescence microscopy (LSFM) is a minimally invasive and high throughput
imaging technique ideal for capturing large volumes of tissue with sub-cellular resolution. A …

GANscan: continuous scanning microscopy using deep learning deblurring

MJ Fanous, G Popescu - Light: Science & Applications, 2022 - nature.com
Most whole slide imaging (WSI) systems today rely on the “stop-and-stare” approach, where,
at each field of view, the scanning stage is brought to a complete stop before the camera …

Deep learning-based single-shot autofocus method for digital microscopy

J Liao, X Chen, G Ding, P Dong, H Ye… - Biomedical Optics …, 2021 - opg.optica.org
Digital pathology is being transformed by artificial intelligence (AI)-based pathological
diagnosis. One major challenge for correct AI diagnoses is to ensure the focus quality of …

Recurrent neural network-based volumetric fluorescence microscopy

L Huang, H Chen, Y Luo, Y Rivenson… - Light: Science & …, 2021 - nature.com
Volumetric imaging of samples using fluorescence microscopy plays an important role in
various fields including physical, medical and life sciences. Here we report a deep learning …