A steady increase of product titers and the corresponding change in impurity composition
represent a challenge for development and optimization of antibody production processes …

This article reviews technology trends in antibody purification. Section 1 discusses non-
chromatography methods, including precipitation, liquid–liquid extraction, and high …

The global antibody market has grown exponentially due to increasing applications in
research, diagnostics and therapy. Antibodies are present in complex matrices (eg serum …

Many successful, recent therapies for life-threatening diseases such as cancer and
rheumatoid arthritis are based on the recognition between native or genetically engineered …

The purification of recombinant proteins by affinity chromatography is one of the most
efficient strategies due to the high recovery yields and purity achieved. However, this is …

Antibodies continue to be extremely utilized entities in myriad applications including basic
research, imaging, targeted delivery, chromatography, diagnostics, and therapeutics. At …

The demand for recombinant therapeutic antibodies and Fc-fusion proteins is expected to
increase in the years to come. Hence, extensive efforts are concentrated on improving the …

Antibodies and related proteins comprise one of the largest and fastest-growing classes of
protein pharmaceuticals. A majority of such molecules are monoclonal antibodies; however …

Antibodies are molecular workhorses in biological research, disease treatment and
diagnostics. Purity is a critical prerequisite for antibody applications. Although protein A …

Targeted nanoparticles of different origins are considered as new-generation diagnostic and
therapeutic tools. However, there are no targeted drug formulations within the composition of …