High‐frequency oscillations as a new biomarker in epilepsy

M Zijlmans, P Jiruska, R Zelmann… - Annals of …, 2012 - Wiley Online Library
The discovery that electroencephalography (EEG) contains useful information at frequencies
above the traditional 80Hz limit has had a profound impact on our understanding of brain …

High-frequency oscillations (HFOs) in clinical epilepsy

J Jacobs, R Staba, E Asano, H Otsubo, JY Wu… - Progress in …, 2012 - Elsevier
Epilepsy is one of the most frequent neurological diseases. In focal medically refractory
epilepsies, successful surgical treatment largely depends on the identification of …

Focal resection of fast ripples on extraoperative intracranial EEG improves seizure outcome in pediatric epilepsy

T Akiyama, B McCoy, CY Go, A Ochi, IM Elliott… - …, 2011 - Wiley Online Library
Summary Purpose: High‐frequency oscillations (HFOs), termed ripples at 80–200 Hz and
fast ripples (FRs) at> 200/250 Hz, recorded by intracranial electroencephalography (EEG) …

[HTML][HTML] High-frequency oscillations in epilepsy and surgical outcome. A meta-analysis

Y Höller, R Kutil, L Klaffenböck… - Frontiers in human …, 2015 - frontiersin.org
High frequency oscillations (HFOs) are estimated as a potential marker for epileptogenicity.
Current research strives for valid evidence that these HFOs could aid the delineation of the …

[HTML][HTML] Electrophysiological biomarkers of epilepsy

RJ Staba, M Stead, GA Worrell - Neurotherapeutics, 2014 - Elsevier
In patients being evaluated for epilepsy and in animal models of epilepsy,
electrophysiological recordings are carried to capture seizures to determine the existence of …

Objective interictal electrophysiology biomarkers optimize prediction of epilepsy surgery outcome

N Kuroda, M Sonoda, M Miyakoshi, H Nariai… - Brain …, 2021 - academic.oup.com
Researchers have looked for rapidly-and objectively-measurable electrophysiology
biomarkers that accurately localize the epileptogenic zone. Promising candidates include …

A storm of fast (40–150 H z) oscillations during hypsarrhythmia in West syndrome

K Kobayashi, T Akiyama, M Oka, F Endoh… - Annals of …, 2015 - Wiley Online Library
Objective Fast oscillations (FOs) were first explored from scalp electroencephalographic
(EEG) data from hypsarrhythmia in West syndrome (infantile spasms) to investigate the …

Interictal high-frequency oscillations generated by seizure onset and eloquent areas may be differentially coupled with different slow waves

Y Nonoda, M Miyakoshi, A Ojeda, S Makeig… - Clinical …, 2016 - Elsevier
Abstract Objective High-frequency oscillations (HFOs) can be spontaneously generated by
seizure-onset and functionally-important areas. We determined if consideration of the …

Universal automated high frequency oscillation detector for real-time, long term EEG

SV Gliske, ZT Irwin, KA Davis, K Sahaya… - Clinical …, 2016 - Elsevier
Objective Interictal high frequency oscillations (HFOs) in intracranial EEG are a potential
biomarker of epilepsy, but current automated HFO detectors require human review to …

Phase‐amplitude coupling between interictal high‐frequency activity and slow waves in epilepsy surgery

H Motoi, M Miyakoshi, TJ Abel, JW Jeong, Y Nakai… - …, 2018 - Wiley Online Library
Objective We hypothesized that the modulation index (MI), a summary measure of the
strength of phase‐amplitude coupling between high‐frequency activity (> 150 Hz) and the …